NCT05151562Recruiting
Music Therapy for Patients With Alzheimer's Disease
Music Therapy for Autobiographical Memory and Neuropsychiatric Symptoms in Alzheimer Disease
Source: ClinicalTrials.gov · Last updated 6 May 2026
Brief summary (registry, in English)
This study is designed to assess the feasibility that individualized reminiscence-based virtual music therapy sessions can enhance autobiographical memory, mood, and cognition in patients with mild cognitive impairment (MCI) or mild dementia due to Alzheimer's Disease (AD). 60 patients with MCI or mild dementia due to AD will receive two 30 minutes reminiscence-targeted virtual music therapy interventions per week for 8 weeks (a total of 16 sessions). Participants' (or supported by the study partner) self-reported and measurable outcomes including cognitive, anxiety, quality of life, and autobiographical memory will be assessed before and after the 8-week course of treatment. Blood-oxygenation level-dependent (BOLD) in functional magnetic resonance imaging (fMRI) will also be also measured before and after the 8-week course of treatment.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 29 Nov 2021
- Start date
- 18 Jul 2022
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- Johns Hopkins University
- Diseases
- Alzheimer disease
- NCT number
- NCT05151562
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 18 Jul 2022 to the primary completion date, 31 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior history as a metal worker and/or certain metallic objects in the body
Other illness
- Medical device incompatible with MRI scanning (e.g. cardiac pacemaker, implanted cardiac defibrillator, aneurysm brain clip, inner ear implant)
Other
- Head trauma, traumatic brain injury, or concussion with loss of consciousness for \>2 minutes
- Claustrophobia incompatible with MRI scanning
- Exclusion Criteria will be carefully determined by the MRI screening form.
Who the study is looking for
- Age 18-89
- Mild Cognitive Impairment (MoCA score: 18-25) or Early AD (MoCA score: 17-24)
Age in the registry: 18 years to 89 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Johns Hopkins School of Medicine Coordinator of this site? Confirm its status | Baltimore | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.