NCT05153785CompletedPhase 2/3
Perioperative Intravenous Lidocaine in Liver Surgery
Intravenous Lidocaine for Postoperative Recovery in Liver Surgery, a Randomized Double Blinded Placebo-controlled Study
Source: ClinicalTrials.gov · Last updated 15 Jan 2026
Brief summary (registry, in English)
This is a randomized double blinded placebo-controlled study, conducted in Lund, Sweden. Patients will be randomized in two groups, with a ratio of 1:1. The experimental arm will receive intravenous Lidocaine perioperatively, and the Control arm will receive placebo, i.e. normal Saline. Postoperative both arms will get routine pain Control with PCA, Patient Controlled Analgesia with an intravenous Oxycodone-infusion. Outcome-measures will include patients pain intensity scoring, and opioid consumption.
- Status (registry)
- Completed
- Phase (registry)
- Phase 2/3
- Study type
- Interventional
- Enrollment
- 124 (actual)
- First submitted
- 12 Nov 2021
- Start date
- 15 Nov 2021
- Primary completion date
- 12 Jun 2025
- Lead sponsor
- Lund University Hospital
- Diseases
- Liver and biliary tract cancer
- NCT number
- NCT05153785
- EudraCT number
- 2019-002361-35
What you commit to
- Study type: Interventional · Phase 2/3
- Participants enrolled: 124
- From 15 Nov 2021 to the primary completion date, 12 Jun 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Treatment with class III anti-arythimic medication
- Use of : Erythromycin, clarithromycin, Fluvoxamine, Cimetidine, ciprofloxacin, antivirala-HIV-läkemedel or imidazol the week before surgery.
Other illness
- Allergy against Lidocain or other amid-type local anasthesia
- Heart failure
- Epilepsy
Other
- Pregnancy
- Cirrosis
- ASA\>3
- Elevated liver enzymes
- AV-block \>1, without pacemaker
- WHO class \>2
- Preoperative ongoing opioid usage
Who the study is looking for
- Age 18 yy
- Patient planned for minor hepatectomy
- Signed informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Skåne University Hospital of Lund Coordinator of this site? Confirm its status | Lund | Sweden | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.