NCT05155501Recruiting
Clinical Trial of Approaches to Prostate Cancer Surgery
Source: ClinicalTrials.gov · Last updated 22 Apr 2026
Brief summary (registry, in English)
This is a prospective, randomized controlled trial to compare cancer control and health-related quality of life following pelvic fascia-sparing radical prostatectomy versus standard radical prostatectomy. The investigators hypothesize that pelvic fascia-sparing radical prostatectomy will have similar cancer control (primary outcome) and sexual function outcomes; and significantly better urinary function, penile shortening/deformity and inguinal hernia risks as compared to radical prostatectomy.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 600 (estimated)
- First submitted
- 30 Nov 2021
- Start date
- 15 May 2023
- Primary completion date
- Jul 2028
- Lead sponsor
- Weill Medical College of Cornell University
- Diseases
- Prostate cancer
- NCT number
- NCT05155501
What you commit to
- Study type: Interventional
- Planned participants: 600
- From 15 May 2023 to the primary completion date, Jul 2028
- 9 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior major pelvic surgery or radiotherapy
Other illness
- Suspicion of N1 disease (i.e., any lymph node greater than 1cm in maximal diameter)
Who the study is looking for
- Male sex
- Age ≥40 years or ≤80 years
- Scheduled for radical prostatectomy for clinically localized prostate cancer
- Able to read and speak English or Spanish
- Willingness to sign informed consent and adhere to the study protocol
Age in the registry: 40 years to 80 years · Sex: Male · Does not accept healthy volunteers
Sites (9)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Johns Hopkins University Coordinator of this site? Confirm its status | Baltimore | United States | Recruiting |
| Beth Israel Deaconess Medical Center (BIDMC) Coordinator of this site? Confirm its status | Boston | United States | Recruiting |
| Northwestern University Coordinator of this site? Confirm its status | Chicago | United States | Recruiting |
| Beckman Research Institute of City of Hope Coordinator of this site? Confirm its status | Duarte | United States | Recruiting |
| NewYork-Presbyterian Queens Coordinator of this site? Confirm its status | Flushing | United States | Recruiting |
| Hackensack Meridian Health Coordinator of this site? Confirm its status | Hackensack | United States | Recruiting |
| Memorial Sloan-Kettering Cancer Center Coordinator of this site? Confirm its status | New York | United States | Recruiting |
| Weill Cornell Medicine Coordinator of this site? Confirm its status | New York | United States | Recruiting |
| Georgetown University Coordinator of this site? Confirm its status | Washington D.C. | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.