NCT05159999Completed
The Home Blood Pressure (BP) Trial
Source: ClinicalTrials.gov · Last updated 20 Jul 2026
Brief summary (registry, in English)
The main study will be a two arm 10-month, cross-over randomized controlled trial of 200 participants treated with end-stage-kidney-disease treated with in-center hemodialysis in the Seattle and San Francisco area comparing a strategy of targeting home vs. pre-dialysis systolic blood pressure \<140 mmHg to reduce rates of intradialytic hypotension. The target systolic blood pressure of \<140 mmHg in both treatment groups will be achieved using an algorithm of dry weight adjustment and anti-hypertensive medication adjustment.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 200 (actual)
- First submitted
- 18 Nov 2021
- Start date
- 2 Feb 2022
- Primary completion date
- 1 Jul 2026
- Lead sponsor
- University of Washington
- Diseases
- Chronic kidney disease
- NCT number
- NCT05159999
What you commit to
- Study type: Interventional
- Participants enrolled: 200
- From 2 Feb 2022 to the primary completion date, 1 Jul 2026
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Pregnant or anticipated pregnancy or breastfeeding (as this will require increase to more than three times a week dialysis and/or preclude use of some classes of blood pressure medications)
Other
- Incarcerated or institutionalized (prohibits home blood pressure measurement)
- Participating in another intervention study that may affect blood pressure
Who the study is looking for
- Aged 18 years or older
- Undergoing in-center, thrice weekly hemodialysis for treatment of end stage renal disease (ESRD)
- Greater than 3 months since initiation of dialysis
- No anticipated change to peritoneal dialysis or kidney transplant within 10 months
- Life expectancy greater than 10 months
- Hypertension (defined as mean pre-dialysis SBP \> 140 mmHg over prior 2 weeks or taking BP medications)
- Able to obtain/measure a brachial blood pressure at dialysis and at home (e.g., no left ventricular assist device, blood pressure not been taken routinely in lower extremity at dialysis unit)
- No condition that the primary nephrologist or PIs feel precludes participation
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of California San Francisco Coordinator of this site? Confirm its status | San Francisco | United States | Unknown status |
| University of Washington Coordinator of this site? Confirm its status | Seattle | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.