NCT05170867Completed
The Impact of Hafnia Alvei on Weight Loss and Glycaemic Control After Bariatric Surgery
The Impact of Hafnia Alvei on Weight Loss and Glycaemic Control After Bariatric Surgery - A Randomized, Triple-blind, Controlled Trial
Source: ClinicalTrials.gov · Last updated 8 May 2026
Brief summary (registry, in English)
This study aims to investigate the effects of Hafnia alvei HA4597 TM supplementation on weight loss and glycemic control after bariatric surgery. Patients undergoing Roux-en-Y gastric bypass will receive probiotics or placebo, twice a day, for 90 days, one month after surgery. Outcomes will be measured at baseline, and 3, 6, 9 and 12 months after the surgery.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 49 (actual)
- First submitted
- 10 Dec 2021
- Start date
- 14 Jan 2022
- Primary completion date
- 31 May 2025
- Lead sponsor
- Universidade Nova de Lisboa
- Diseases
- Obesity, Type 2 diabetes
- NCT number
- NCT05170867
What you commit to
- Study type: Interventional
- Participants enrolled: 49
- From 14 Jan 2022 to the primary completion date, 31 May 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Intake of antibiotics and/or probiotics in the previous 12 weeks
- Weight change \>5% in the previous 12 weeks
Other illness
- Diagnosis of gastrointestinal disease or other significant illness
Other
- Pregnancy or breastfeeding
Who the study is looking for
- Men and women between 18 and 65 years
- BMI ≥35 kg/m2 and at least one severe obesity-related complications, or BMI ≥40 kg/m2
- Undergoing Roux-en-Y gastric bypass
- Willing to take a probiotic/placebo supplement twice a day for 60 days
- Willing and able to provide written informed
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| NOVA Medical School|Faculdade de Ciências Médicas, Universidade NOVA de Lisboa Coordinator of this site? Confirm its status | Lisbon | Portugal | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.