NCT05175651Not yet recruiting
Prospective Electronic Polygenic Risk Study - Second Phase
Source: ClinicalTrials.gov · Last updated 7 Nov 2022 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This study will investigate the role of polygenic risk scores (PRS) in preventive health.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 10000 (estimated)
- First submitted
- 29 Nov 2021
- Start date
- Jun 2023
- Primary completion date
- 15 Jan 2025
- Lead sponsor
- Scripps Translational Science Institute
- Diseases
- Coronary artery disease, Glaucoma
- NCT number
- NCT05175651
What you commit to
- Study type: Interventional
- Planned participants: 10000
- From Jun 2023 to the primary completion date, 15 Jan 2025
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior diagnosis of coronary disease as defined by prior myocardial infarction (STEMI or NSTEMI), or revascularization (stent or coronary artery bypass grafting)
- Prior diagnosis or treatment of glaucoma
- Anti-PCSK9 therapy
- Lipid apheresis therapy
- Currently enrolled in a clinical trial for lipid lowering therapy
Other illness
- Cerebrovascular disease with history of ischemic stroke, TIA, carotid endarterectomy, carotid artery stenting
- Peripheral arterial disease with history of claudication, revascularization (stents or bypass)
Other
- Current and active high-intensity statin prescription (rosuvastatin 20 mg, rosuvastatin 40 mg, atorvastatin 40 mg and atorvastatin 80 mg)
- Known statin intolerance to 2 or more statins in the past
Who the study is looking for
- 45 ≥ Age \< 65
- ASCVD Risk Score \> 7.5% as defined by the standard pooled cohort equation
- Access to and ability to use a smartphone
Age in the registry: 45 years to 65 years · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.