NCT05177523Recruiting
Imaging the Interplay Between Axonal Damage and Repair in Multiple Sclerosis
INsIDER: Imaging the Interplay Between Axonal Damage and Repair in Multiple Sclerosis
Source: ClinicalTrials.gov · Last updated 16 Dec 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This project is to: 1. Quantify differences in axonal integrity and organization in aMS versus naPMS patients. 2. Quantify changes in axonal integrity and organization in aMS versus naPMS patients over a two-year period. 3. Validate the combination of imaging parameters that best differentiate aMS versus naPMS patients using histopathology.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 300 (estimated)
- First submitted
- 15 Dec 2021
- Start date
- 4 Sept 2018
- Primary completion date
- Dec 2028
- Lead sponsor
- University Hospital, Basel, Switzerland
- Diseases
- Multiple sclerosis
- NCT number
- NCT05177523
What you commit to
- Study type: Observational
- Planned participants: 300
- From 4 Sept 2018 to the primary completion date, Dec 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Contraindication to MRI (eg, claustrophobia, metallic implants, pacemaker etc).
Other
- Pregnancy
- Inability to give consent
Who the study is looking for
- Patients may be diagnosed with:
- active RRMS (n=100): Relapsing-remitting course and \> 1 clinical relapse and/or signs of MRI activity (\> 1 Gd enhancing lesion) during the last year before study enrollment.
- non-active PMS (n=100): Progressive course (PPMS or SPMS) and no clinical relapses and/or signs of MRI activity during the last year before study enrollment.
- Age 18-80 years old
- No other neurological or psychiatric disorder
- Age 18-80 years old
- No other neurological or psychiatric disorder
Age in the registry: 18 years to 80 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospital Basel, Department of Neurology Coordinator of this site? Confirm its status | Basel | Switzerland | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.