Toxicity of Micro and Nano Plastics Combined With Environmental Contaminants on the Risk of Allergic Disease

Prior treatment

• Oxygen therapy after birth with a duration of more than 24 h
• Fever of at least 38.5 °C during the last two weeks prior to the planned visit

Other illness

• Known inborn or perinatal pulmonary disease;
• Heart failure diagnosed after birth affecting pulmonary circulation
• Major respiratory diseases such as e.g. interstitial lung disease and other congenital and serious chronic disease

Other

• Pulmonary malformation
• Ventilator support or mechanical ventilation after birth
• Diagnosis of cystic fibrosis
• Primary ciliary dyskinesia

• Proven sensitization to at least one food allergen with a diagnosis of at least one allergic disease for at least one year
• Clinical diagnosis of allergic rhinitis (AR) for at least 1 year with symptoms of the nose, induced after exposure to allergens via IgE-mediated hypersensitivity reactions (symptoms of watery rhinorrhea, nasal obstruction, nasal itching and sneezing).
• Diagnosis of atopic dermatitis (AD) with AD symptoms lasting for more than 3 months, with or without food allergy
  • Additional inclusion criteria:
• Significant clinical allergy to indoor and outdoor allergens, an food allergens with positive skin prick test (SPT) and specific IgE levels (\>0.35kUA/L)