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NCT05179187Active, not recruiting

Non-invasive Brain Mapping of Movement Facilitation in Parkinson's Disease

Source: ClinicalTrials.gov · Last updated 15 Oct 2026

Brief summary (registry, in English)

Several strategies or contexts help patients with Parkinson's disease to move more quickly or normally, however the brain mechanisms underlying these phenomena are poorly understood. The proposed studies use complimentary brain mapping techniques to understand the brain mechanisms supporting improved movements elicited by external cues. The central hypothesis is that distinct networks are involved in movement improvement depending on characteristics of the facilitating stimulus. Participants will perform movement tasks during recording of brain activity with EEG and MRI. The identified biomarkers may provide targets for future neuromodulation therapies to improve symptoms that are refractory to current treatments, such as freezing of gait.

Status (registry)
Active, not recruiting
Study type
Interventional
Enrollment
90 (estimated)
First submitted
16 Dec 2021
Start date
6 Jul 2022
Primary completion date
1 Sept 2026
Lead sponsor
University of California, Los Angeles
NCT number
NCT05179187

What you commit to

  • Study type: Interventional
  • Planned participants: 90
  • From 6 Jul 2022 to the primary completion date, 1 Sept 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Contraindications to MRI (metal implant, claustrophobia)

Other illness

  • Dementia as indicated by score on Montreal Cognitive Assessment \< 19

Other

  • Active hallucinations or psychosis

Who the study is looking for

  • Diagnosis of Parkinson's disease based on presence of at least 2 cardinal features (tremor, rigidity or bradykinesia) OR healthy adult with no neurologic disease
  • Age \> 18 years old

Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
University of California, Los Angeles
Coordinator of this site? Confirm its status
Los AngelesUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.