NCT05182229Active, not recruiting
Comparing Two Ways to Manage Head and Neck Lymphedema
Comparing Two Ways to Manage Lymphedema in Head and Neck Cancer Survivors
Source: ClinicalTrials.gov · Last updated 6 May 2026
Brief summary (registry, in English)
This randomized clinical trial aims to compare clinic-based CDT and home-based (a hybrid model) CDT on changes in the severity of lymphedema, symptom burden, functional status, and healthcare utilization in HNC survivors with lymphedema.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 240 (actual)
- First submitted
- 12 Dec 2021
- Start date
- 11 Mar 2022
- Primary completion date
- 30 Jun 2027
- Lead sponsor
- Abramson Cancer Center at Penn Medicine
- Diseases
- Head and neck cancer
- NCT number
- NCT05182229
What you commit to
- Study type: Interventional
- Participants enrolled: 240
- From 11 Mar 2022 to the primary completion date, 30 Jun 2027
- 6 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Active infection in soft tissues in the head and neck region
- History of moderate or severe carotid artery occlusion
- Conditions impacting the safe delivery of lymphedema therapy
Other
- Significantly severe lymphedema (e.g., severe periorbital swelling)
Who the study is looking for
- \>18 years of age
- \<=24 months post-HNC treatment
- Diagnosis of head and neck lymphedema and referral by their oncology providers
- Able to perform self-manual lymphatic drainage
- Having an electronic device (a computer, tablet, iPad, laptop, or smartphone) and internet access at home
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (6)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Jefferson Cherry Hospital Jefferson Health Coordinator of this site? Confirm its status | Cherry Hill | United States | Unknown status |
| University of Pennsylvania Coordinator of this site? Confirm its status | Philadelphia | United States | Unknown status |
| Jefferson Torresdale Hospital Jefferson Health Coordinator of this site? Confirm its status | Philadelphia | United States | Unknown status |
| Temple University Hospital and Fox Chase Cancer Center Coordinator of this site? Confirm its status | Philadelphia | United States | Unknown status |
| Jefferson Health Coordinator of this site? Confirm its status | Philadelphia | United States | Unknown status |
| Asplundh Cancer Pavilion Jefferson Health Coordinator of this site? Confirm its status | Willow Grove | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.