NCT05184933Recruiting
Sleep and Circadian Mechanisms in Hypertension
Source: ClinicalTrials.gov · Last updated 11 Feb 2026
Brief summary (registry, in English)
This study is a mechanistic clinical trial designed to investigate the effects of the circadian system and sleep on non-dipping blood pressure (BP) in people with hypertension (HTN).
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 32 (estimated)
- First submitted
- 22 Dec 2021
- Start date
- 4 Aug 2022
- Primary completion date
- 31 Mar 2028
- Lead sponsor
- Oregon Health and Science University
- Diseases
- High blood pressure
- NCT number
- NCT05184933
What you commit to
- Study type: Interventional
- Planned participants: 32
- From 4 Aug 2022 to the primary completion date, 31 Mar 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior shift work within 12 months prior to the study;
- History of heart failure, cardiomyopathy, or history of bypass surgery, angioplasty, or previous myocardial infarction;
- Prescription medications (Contraceptives and anti-hypertensive medications are permissible);
- 30 days free of cannabis use prior to the study;
Other illness
- Acute or chronic diseases (except hypertension) that may affect outcome measures;
- History of psychological conditions;
- Sleep disorders, like severe sleep apnea, insomnia, etc.;
- History of Illicit drug use and alcohol dependency;
Other
- Over 5 pack-years of smoking;
- Travel greater than three time zones for at least 3 months;
- Pregnancy;
- Upper cut-off of 160/100 mmHg for BP
Who the study is looking for
- Ages 25-64
- BMI 18.5-42kg/m2
- Hypertension (average resting blood pressure between 130/80 mmHg and 160/100 mmHg)
Age in the registry: 25 years to 64 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Oregon Health and Science University Coordinator of this site? Confirm its status | Portland | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.