NCT05188066Not yet recruiting
Study of Pregnancy Pathologies Associated With Placental Abnormalities
Source: ClinicalTrials.gov · Last updated 12 Jan 2022 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Pregnancy pathologies can occur from implantation until childbirth. The investigators are interested in the development mechanisms of these pathologies and aim to develop therapies to treat them. The investigators need to collect samples, especially placental samples, following abortions and term and premature deliveries. Abortions will allow investigators to have non-pathological placental material up to 13 weeks. This material will serve as a reference for the understanding of the histological changes that occur in normal placentas collected at term of pregnancy. The latter will, in turn, be compared with the placentas collected during premature deliveries. Also, the abortion product will be cultivated in an environment mimicking the pathology of pre-eclampsia. This study will allow investigators to advance their understanding of the pathophysiological mechanisms of the placenta. The investigators are internationally recognized for their research on these pathologies.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 800 (estimated)
- First submitted
- 18 Dec 2021
- Start date
- 6 Jan 2022
- Primary completion date
- 31 Jan 2027
- Lead sponsor
- University Hospital, Grenoble
- NCT number
- NCT05188066
What you commit to
- Study type: Observational
- Planned participants: 800
- From 6 Jan 2022 to the primary completion date, 31 Jan 2027
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patient with known positive HIV or Hepatitis B or Hepatitis C serology or at risk according to the infectious safety criteria applied by the EFS.
Lab values
- hemoglobin \<7d / dL or hemoglobin \<10g / dL if she suffers from a cardio-respiratory pathology).
Other
- Placental sample or abortion product unavailable (not collected or necessary for treatment).
- Patient protected by law (minor, hospitalized under duress, subject to a legal protection measure by guardianship or curatorship, deprived of liberty by judicial or administrative decision)
Who the study is looking for
- Adult women
- Admitted to the CHUGA for a birth or an abortion.
- Pregnant women consenting to the collection of their fetal placenta membranes, during premature deliveries or at term of pregnancy OR Women performing an abortion consenting to the collection of their abortion products.
- Having signed a consent
- Affiliated with social security
Age in the registry: 18 years to 52 years · Sex: Female · Accepts healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.