NCT05190666Active, not recruiting
Healthy Living After Knee Replacement
Physical Activity and Weight Loss to Improve Function and Pain After Total Knee Replacement
Source: ClinicalTrials.gov · Last updated 3 Nov 2026
Brief summary (registry, in English)
The purpose of this study is to examine if a weight loss program designed for adults after knee replacement improves weight loss, physical activity, pain, and function, as well as if the program is cost effective, as compared to a chronic disease self-management program.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 182 (actual)
- First submitted
- 28 Dec 2021
- Start date
- 4 Jan 2022
- Primary completion date
- 17 Jun 2026
- Lead sponsor
- University of South Carolina
- Diseases
- Obesity
- NCT number
- NCT05190666
What you commit to
- Study type: Interventional
- Participants enrolled: 182
- From 4 Jan 2022 to the primary completion date, 17 Jun 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- are taking anti-obesity medications
- had or are planning to have bariatric/gastric/lap band surgery
Other illness
- have a mobility limiting comorbidity unrelated to knee replacement (e.g. spinal stenosis, fibromyalgia, peripheral vascular disease, stroke)
Other
- have any contraindications to diet or weight loss
- undergo simultaneous bilateral knee replacement or have a scheduled or anticipated knee replacement for the contralateral knee within the next 18 months
- are enrolled in a formal weight loss program
- are planning to relocate out of the Columbia or Greenville, SC areas in the next 18 months.
Who the study is looking for
- Participants must:
- have a body mass index between 25-45 kg/m2
- have had a knee replacement (including primary, staged or independent bilateral, or revision) \<6 months prior to baseline assessment
- have a computer, tablet, or smartphone with active internet access to self-monitor online and/or have a device or computer compatible with Fitbit
- completion of baseline assessment measures (height, weight, function tests, surveys, ≥4 days valid of activity monitoring, and 1 day of dietary recall)
- be English-speaking and able to read consent and study materials written in English
- be willing to attend 4 in-person assessments.
Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of South Carolina Coordinator of this site? Confirm its status | Columbia | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.