NCT05191186CompletedPhase 3
Documentation of Efficacy of Intralymphatic Allergen Immunotherapy
Documentation of Efficacy of Intralymphatic Allergen Immunotherapy in a Phase III Randomized, Parallel Group Placebo Controlled Double Blind Multisite Field Trial
Source: ClinicalTrials.gov · Last updated 12 Aug 2025
Brief summary (registry, in English)
Investigation of the clinical efficacy of 3 intralymphatic injections with grass pollen extract into inguinal lymph nodes on combined symptom-medication scores during grass pollen season in grass pollen allergic patients compared to placebo
- Status (registry)
- Completed
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 450 (actual)
- First submitted
- 27 Dec 2021
- Start date
- 1 Feb 2020
- Primary completion date
- 1 Aug 2023
- Lead sponsor
- Aarhus University Hospital
- Diseases
- Asthma
- NCT number
- NCT05191186
What you commit to
- Study type: Interventional · Phase 3
- Participants enrolled: 450
- From 1 Feb 2020 to the primary completion date, 1 Aug 2023
- 2 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- previous AIT for grass pollen allergy
- planned depot steroid injections during season
Other illness
- significant mugwort allergy
- uncontrolled non-allergic upper airways disease
- uncontrolled autoimmune diseases
- active malignancies
- uncontrolled other severe condition, including psychiatric diseases
Other
- uncontrolled asthma
Who the study is looking for
- moderate-severe grass pollen allergic rhinoconjunctivitis
- positive skin prick test for grass pollen extract
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Aarhus University Hospital Coordinator of this site? Confirm its status | Aarhus | Denmark | Unknown status |
| Linkoeping University Hospital Coordinator of this site? Confirm its status | Linköping | Sweden | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.