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NCT05194566Recruiting

Neurostimulation for the Treatment of Post-Stroke Aphasia

Source: ClinicalTrials.gov · Last updated 18 Feb 2026

Brief summary (registry, in English)

The aim of the trial is to determine whether 75Hz transcranial alternating current stimulation (tACS) synchronized with therapeutic linguistic tasks is an effective form of therapy for post-stroke aphasia.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
64 (estimated)
First submitted
4 Jan 2022
Start date
6 Sept 2023
Primary completion date
Dec 2026
Lead sponsor
QVITI S.A.
Diseases
Stroke
NCT number
NCT05194566

What you commit to

  • Study type: Interventional
  • Planned participants: 64
  • From 6 Sept 2023 to the primary completion date, Dec 2026
  • 2 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • presence of metal implants in the skull.
  • other previously absent neurological or mental symptoms
    • Withdrawal criteria:
  • other previously absent neurological, physical or mental symptoms.

Other illness

  • severe cognitive, auditory or visual impairment that would preclude cognitive and language testing - inability to follow a two-step command.
  • presence of major untreated or unstable psychiatric disease.
  • history of epilepsy or seizures.
  • ongoing medication that increases the risk of epileptic seizures.
  • presence in the body of cardiac stimulator, pacemaker or vagus nerve stimulator (implanted).
  • history of speech, language, hearing, or intellectual disability during childhood.
  • occurrence of an epileptic seizure.
  • occurrence of an epileptic seizure;

Other

  • pregnancy (based on declarations)
  • high intolerance to stimulation.
  • high intolerance to stimulation (participants experience severe discomfort during stimulation);

Who the study is looking for

  • diagnosis of aphasia: Broca's or mixed (based on the assessment of a Speech Language Pathologist).
  • presence of a focus of injury in the left hemisphere (within one hemisphere only) as a result of the first ischemic or hemorrhagic stroke (based on CT/MRI examination);
  • chronic stage of the disease - time since the stroke occurred over 6 months.
  • ability to achieve an accuracy in the Naming Task of 10-60%.
  • 18-80 years
  • right-handedness before the stroke.
  • ability to give informed written consent.
  • fluency in English.

Criteria the registry did not label

  • Individuals with aphasia (assessed using the Boston Diagnostic Aphasia Examination) who perform the Naming Task in the range of 10%-60% accuracy will be included in the study. The overall baseline score in the Naming Task will be estimated from the two baseline measurements.

Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (2)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Think & Speak Lab at Shirley Ryan AbilityLab
Coordinator of this site? Confirm its status
ChicagoUnited StatesRecruiting
Abilities Research Center at Mount Sinai
Coordinator of this site? Confirm its status
New YorkUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.