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NCT05201534Recruiting

Interventions in Mathematics and Cognitive Skills

Interventions in Math Learning Disabilities: Cognitive and Neural Correlates

Source: ClinicalTrials.gov · Last updated 11 Aug 2026

Brief summary (registry, in English)

The purpose of this study is to investigate neurocognitive mechanisms underlying response to intervention aimed at enhancing, and remediating weaknesses in, numerical skills in children, including those with mathematical learning disabilities (MLD).

Status (registry)
Recruiting
Study type
Interventional
Enrollment
180 (estimated)
First submitted
7 Jan 2022
Start date
5 May 2023
Primary completion date
31 Aug 2027
Lead sponsor
Stanford University
NCT number
NCT05201534

What you commit to

  • Study type: Interventional
  • Planned participants: 180
  • From 5 May 2023 to the primary completion date, 31 Aug 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Exclusion from MRI scan session: No major contraindication for magnetic resonance imaging (MRI) - braces, metal implants, pacemakers, vascular stents, metallic ear tubes, consistent exposure to metal, claustrophobia)

Other illness

  • History of neurological or psychiatric disorder (i.e., schizophrenia, psychosis, depression, or attention deficit hyperactivity disorder.)
  • History of trauma involving head injury
  • Consistent psychiatric medications

Who the study is looking for

  • Elementary school aged children starting from first grade (6-12 years old)
  • IQ: Participants with a Full Scale IQ \> 70 on the Wechsler Abbreviated Scle of Intelligence (WASI-II).
  • Identification of Mathematical Learning Disabilities: Scores below the 35th percentile percentile on symbolic number processing test in Numeracy Screener and two or more Wechsler Individual Achievement Test (WIAT-IV) math subtests
  • Identification of typically developing children: Scores at or above the 35th percentile percentile on symbolic number processing test in Numeracy Screener and all WIAT-IV math subtests
  • Normal or corrected-to-normal vision and no hearing impairments
  • Inclusion in MRI scan session: Right-handed

Age in the registry: 6 years to 12 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Stanford Cognitive and Systems Neuroscience Laboratory
Coordinator of this site? Confirm its status
Palo AltoUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.