NCT05203523Completed
Investigational Dementia Treatment Study
Investigating the Effect of Cognitive Training with and Without Transcranial Alternating Current Stimulation on the Executive Brain Functions in Dementia Population
Source: ClinicalTrials.gov · Last updated 13 Mar 2025
Brief summary (registry, in English)
This research investigates the effect of active versus sham tACS paired with cognitive exercises in a regimen protocol of weeks, everyday. The study design is a one-time crossing over design in which participants are randomized into two groups: One group will receive active treatment for 4 weeks, then 8 weeks of no treatment followed by another 4 weeks of treatment but with sham. The other group will start with sham and end up with active treatment. The study is double-blind; thus, neither participants, nor the assessors know the group assignment. The Intervention is applying tACS either active or sham paired with cognitive exercises (MindTriggers app games). Note: The above study will run at both University of Manitoba (U of M) and Aster Gardens residence. However, at Aster Gardens Residence only questionnaire type of assessments will be run, while in U of M, the investigators will have three other major assessments as well. In addition, the investigators will run the assessments at the Aster Gardens Residence through online sessions.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 73 (actual)
- First submitted
- 3 Oct 2021
- Start date
- 24 Jan 2022
- Primary completion date
- 6 Dec 2024
- Lead sponsor
- University of Manitoba
- NCT number
- NCT05203523
What you commit to
- Study type: Interventional
- Participants enrolled: 73
- From 24 Jan 2022 to the primary completion date, 6 Dec 2024
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Plan to change the medication during this study's period
Other illness
- Being diagnosed with Parkinson's, Parkinsonian dementia, Huntington disease, speech significant aphasia and intellectual disability, major depression/anxiety, bipolar disorder, schizophrenia or any other major mood disorder
- Having a History of epileptic seizures or epilepsy
- Current substance abuse disorder
- Currently participating in another therapeutic study for dementia
Other
- Inability to adequately communicate in English
- Impaired vision or hearing severe enough to impair performance in cognitive tests
Who the study is looking for
- ability to read, write and speak English fluently
Age in the registry: 50 years to 95 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Aster Gardens Coordinator of this site? Confirm its status | Edmonton | Canada | Unknown status |
| Riverview Health Centre Coordinator of this site? Confirm its status | Winnipeg | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.