NCT05211882Completed
ENABLE (Educate, Nurture, Advise, Before Life Ends) Intervention for Heart Failure (HF) Patients and Their Caregivers in Singapore
Pilot Wait-list Randomized Controlled Trial of the ENABLE (Educate, Nurture, Advise, Before Life Ends) Intervention for Heart Failure (HF) Patients and Their Caregivers in Singapore
Source: ClinicalTrials.gov · Last updated 3 Sept 2025
Brief summary (registry, in English)
To pilot a culturally adapted version of ENABLE (6-month program) for Heart Failure (HF) patients and caregivers in the inpatient and outpatient setting in Singapore. The investigators aim to determine the feasibility of trial procedures and assess the acceptability and preliminary efficacy of ENABLE with a randomized wait-list controlled trial design.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 125 (actual)
- First submitted
- 2 Jan 2022
- Start date
- 14 Feb 2022
- Primary completion date
- 25 Sept 2024
- Lead sponsor
- National Cancer Centre, Singapore
- Diseases
- Heart failure
- NCT number
- NCT05211882
What you commit to
- Study type: Interventional
- Participants enrolled: 125
- From 14 Feb 2022 to the primary completion date, 25 Sept 2024
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Exclusion criteria for patients:
- Patients who are unable to give informed consent
- Patients who are already known to a palliative care service.
- Exclusion criteria for caregivers:
- Caregivers who are unable to give informed consent.
- Caregivers who are domestic helpers.
Who the study is looking for
- Inclusion criteria for patients:
- 21 years or older.
- Able to communicate in English or Chinese.
- Have a diagnosis of HF (stage C or D) by the American College of Cardiology guidelines and be of New York Heart Association (NYHA) stage 2, 3 or 4 functional statuses.
- Have an expected prognosis of at least 6 months.
- Be on disease directed HF management.
- Have had a hospitalization event within 6 months prior to recruitment.
- Inclusion criteria for caregivers:
- 21 years or older.
- Able to communicate in English or Chinese.
- Is a direct family caregiver of the patient.
Age in the registry: 21 years to 99 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| National Heart Centre Singapore Coordinator of this site? Confirm its status | Singapore | Singapore | Unknown status |
| National Cancer Centre Singapore Coordinator of this site? Confirm its status | Singapore | Singapore | Unknown status |
Related publications
- Feasibility, acceptability and efficacy of a nurse-led palliative care health coaching intervention (Educate, Nurture, Advise before Life Ends) for patients with heart failure and their caregivers in Singapore: a randomised wait-list controlled pilot study of health coaching in Asian heart failure.BMJ Open · 2026 · PMID 42152453
- Navigating life with heart failure: Patient and caregiver perspectives of the culturally adapted Educate, Nurture, Advise, Before Life Ends health coaching programme.Palliat Care Soc Pract · 2026 · PMID 41947874
This page is information, not medical advice. Discuss any trial with your doctor.