NCT05220345Completed
Synergistic Effect of G-Eye Balloon for Behind the Folds Visualization With CADe (Discovery System) on Adenoma Detection Rate.
Synergistic Effect of G-Eye Balloon for Behind the Folds Visualization With Artificial Intelligence Assisted Polyp Detection (Discovery System) on Adenoma Detection Rate. 'Discovery III Study'
Source: ClinicalTrials.gov · Last updated 15 Aug 2025
Brief summary (registry, in English)
Colonoscopy is the gold standard for colorectal screening. The diagnostic accuracy of colonoscopy highly depends on the quality of inspection of the colon during the procedure. To increase detection new polyp detection systems based on artificial intelligence (AI) have been developed. However, these systems still depend on the ability of the endoscopist to adequately visualize the complete colonic mucosa, especially to detect smaller and more subtle lesions, or lesions hidden behind folds in the colon. With this study we want to combine a device to flatten the folds in the colon combined with an artificial intelligence system to further improve the detection rate of lesions during colonoscopy.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 196 (actual)
- First submitted
- 31 Jan 2022
- Start date
- 12 May 2022
- Primary completion date
- 26 Aug 2024
- Lead sponsor
- Radboud University Medical Center
- NCT number
- NCT05220345
What you commit to
- Study type: Interventional
- Participants enrolled: 196
- From 12 May 2022 to the primary completion date, 26 Aug 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Therapeutic procedure (e.g., endoscopic mucosal resection)
- Prior surgical resection of any portion of the colon
Other illness
- Inflammatory bowel disease (IBD)
- Inadequately corrected anticoagulation disorder or anticoagulation medication use
Other
- Known polyp or tumor upon referral
- American Society of Anesthesiologists score of ≥3
- inability to provide informed consent.
Who the study is looking for
- Adult patients (\>18 years)
- Referred and scheduled for diagnostic, screening (non-iFOBT based), or surveillance colonoscopy.
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Radboud university medical center Nijmegen Coordinator of this site? Confirm its status | Nijmegen | Netherlands | Unknown status |
Related publications
- Effect of Combination of a Mucosal Exposure Device and Computer-Aided Detection in Diagnostic, Screening, and Surveillance Colonoscopy: An International, Multicenter Study.Clin Transl Gastroenterol · 2026 · PMID 41363762
This page is information, not medical advice. Discuss any trial with your doctor.