NCT05227092Recruiting
3D OPTIMIZED WMN MPRAGE Increased Detection of Focal Spinal Cord Lesion in Multiple Sclerosis (WHINUME)
Source: ClinicalTrials.gov · Last updated 29 Jun 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The aim of this study is to compare the 3D OPTIMIZED MPRAGE WMN sequence to "conventional sequences" used in spinal cord analysis. The patients will be explored at the cervical level with the conventional 2D sagittal T2 FSE, 2D sagittal STIR, 2D sagittal PSIR, 3D T1 MPRAGE sequences, and the sequence of interest 3D sagittal OPTIMIZED WMN MPRAGE and 3D axial OPTIMIZED WMN MPRAGE. At the thoracic level, with the conventional 2D sagittal T2 FSE, 2D sagittal STIR, 3D T1 MPRAGE sequences and the sequence of interest 3D sagittal OPTIMIZED WMN MPRAGE.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 26 Jan 2022
- Start date
- 2 Aug 2023
- Primary completion date
- 1 May 2026
- Lead sponsor
- University Hospital, Bordeaux
- Diseases
- Multiple sclerosis
- NCT number
- NCT05227092
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 2 Aug 2023 to the primary completion date, 1 May 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Surgical history on the spinal cord or lumbar spine
Other illness
- Other diagnosis (Neuro-myelitis spectrum disease or Progressive Multiple Sclerosis)
Other
- Pregnant or potentially pregnant women
- Breastfeeding woman
- Contraindications to MRI
- Patient under legal protection
Who the study is looking for
- Patients older than 18 years old
- CIS or RRMS
- Medullary symptomatology less than 6 months
- With or without an objective lesion on a subsequent MRI scan
- Signed the Informed Consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHU de Bordeaux Coordinator of this site? Confirm its status | Bordeaux | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.