NCT05230628Active, not recruiting
Auricular Vagus Stimulation in Obesity
The Effectiveness of Transcutaneous Electrical Nerve Stimulation of the Auricular Branch of the Vagus Nerve in Loss Weight and Improving the Quality of Life in Patients With Obesity
Source: ClinicalTrials.gov · Last updated 3 Sept 2025
Brief summary (registry, in English)
Transcutaneous vagus nerve stimulation (TENS) involves stimulation of the left and/or right auricular branch of the vagus nerve with low-frequency electrical impulses. In recent years, the possibilities of using this technology in chronic conditions characterized by immune and metabolic dysregulation have been studied. The aim of this study is to investigate the effectiveness of TENS in reducing weight and improving quality of life in patients with various degrees of obesity.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 131 (actual)
- First submitted
- 28 Jan 2022
- Start date
- 4 Apr 2022
- Primary completion date
- 31 Jan 2026
- Lead sponsor
- National Medical Research Center for Therapy and Preventive Medicine
- Diseases
- Obesity
- NCT number
- NCT05230628
What you commit to
- Study type: Interventional
- Participants enrolled: 131
- From 4 Apr 2022 to the primary completion date, 31 Jan 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Presence of an electrically, magnetically or mechanically activated implant, an intracerebral vascular clip, or any other electrically sensitive support system.
Other illness
- Cardiac arrhythmias: bradyarrhythmias, Atrioventricular blockades of any degree;
Other
- Taking beta blockers;
- The endocrine nature of obesity;
- Expected technical difficulties when using the device on the part of the patient;
- Pregnant or plan on becoming pregnant or breastfeeding during the study period;
Who the study is looking for
- Adult patients with grade 1-2 nutritional obesity who are willing and able to give informed written consent to participate in the study, are on sinus rhythm and are not taking any antiarrhythmic drugs, including beta-blockers.
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| National Medical Research Center for Therapy and Preventive Medicine Coordinator of this site? Confirm its status | Moscow | Russia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.