NCT05230784Recruiting
The PURI-HF (Air Purifiers on Heart Failure) Trial
Effectiveness of Indoor Air Purifiers on Heart Failure Outcomes
Source: ClinicalTrials.gov · Last updated 29 Jan 2026
Brief summary (registry, in English)
Indoor air pollution and fine mode particulate matter with an aerodynamic diameter smaller than 2.5 micrometers (PM2.5) is a major contributor to global morbidity and mortality, particularly due to cardiovascular disease. This project aims to demonstrate the efficacy, feasibility and effectiveness of portable air filters in improving indoor PM2.5 levels and improving functional capacity of heart failure patients with reduced ejection fraction in India. The findings from the project will add to existing knowledge of innovative and scalable strategies to improve environmental and cardiovascular health worldwide. The overall objective of this study is to demonstrate the efficacy, feasibility, and effectiveness of portable air filters in improving indoor PM2.5 levels and improving functional capacity of heart failure patients with reduced ejection fraction in India.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 255 (estimated)
- First submitted
- 29 Jan 2022
- Start date
- 6 Mar 2024
- Primary completion date
- 29 Feb 2028
- Lead sponsor
- NYU Langone Health
- Diseases
- Heart failure
- NCT number
- NCT05230784
What you commit to
- Study type: Interventional
- Planned participants: 255
- From 6 Mar 2024 to the primary completion date, 29 Feb 2028
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- on oxygen therapy
Other illness
- listed for a cardiac transplant
- history of CRT device implantation in last 3 months
- with severe pulmonary disease
Other
- participants unable to ambulate
Who the study is looking for
- Adults ≥ 18 years of age diagnosed with HF with a reduced ejection fraction of ≤ 40% within the last six months in NYHA class II-IV.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| All India Institute of Medical Sciences (AIIMS) Coordinator of this site? Confirm its status | Delhi | India | Recruiting |
| Public Health Foundation of India (PHFI) Coordinator of this site? Confirm its status | Ludhiana | India | Recruiting |
| Centre for Chronic Disease Control (CCDC) Coordinator of this site? Confirm its status | Thiruvananthapuram | India | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.