NCT05231915Completed
Prevalence of the c.853delT Mutation of the HOXB13 Gene in Prostate Cancer in Martinique
Source: ClinicalTrials.gov · Last updated 31 Mar 2026
Brief summary (registry, in English)
In Martinique, prostate cancer incidence rates are nowadays among the highest worldwide with a high incidence of early-onset and familial forms. We identified a rare heterozygous germline variant c.853delT (p.Ter285Lysfs) rs77179853, reported only among patients of African ancestry with a minor allele frequency of 3.2%. We search to estimate the prevalence of this variant in a sample of prevalent prostate cancer cases managed in urology consultation in Martinique .
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 465 (actual)
- First submitted
- 1 Feb 2022
- Start date
- 9 Apr 2021
- Primary completion date
- 27 Nov 2024
- Lead sponsor
- University Hospital Center of Martinique
- Diseases
- Prostate cancer
- NCT number
- NCT05231915
What you commit to
- Study type: Interventional
- Participants enrolled: 465
- From 9 Apr 2021 to the primary completion date, 27 Nov 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Patient who is not of African descent
- Refusal to participate.
- Patients not affiliated to french social security
Who the study is looking for
- Adult man over 18 years of age living in Martinique with a prostate cancer whatever the histological type and the stage, managed in urology consultation (public and private sectors of Martinique)
- Sporadic or familial form
- Informed with a written consent signed by the participant and the investigator
- Affiliate or beneficiary of french social security.
Age in the registry: 18 years to - · Sex: Male · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Centre Hospitalier Universitaire de Martinique Coordinator of this site? Confirm its status | Fort-de-France | Martinique | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.