NCT05234177Recruiting
Tempus CRC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With CRC Using NGS Assays
Tempus CRC Surveillance Study: A Longitudinal Circulating Tumor DNA (ctDNA) Biomarker Profiling Study of Patients With Colorectal Cancer (CRC) Using Comprehensive Next-Generation Sequencing (NGS)Assays
Source: ClinicalTrials.gov · Last updated 6 May 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The study is an observational multicenter evaluation of participants with colorectal cancer (CRC) who will receive longitudinal plasma ctDNA biomarker profiling in addition to their standard-of-care therapy and disease surveillance.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 300 (estimated)
- First submitted
- 31 Jan 2022
- Start date
- 21 Jun 2022
- Primary completion date
- Feb 2027
- Lead sponsor
- Tempus AI
- Diseases
- Colorectal cancer
- NCT number
- NCT05234177
What you commit to
- Study type: Observational
- Planned participants: 300
- From 21 Jun 2022 to the primary completion date, Feb 2027
- 20 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Not willing to have additional blood samples collected
- Pathology that is not consistent with colorectal adenocarcinoma
Who the study is looking for
- Known or suspected colorectal adenocarcinoma (Stage I to IVA disease)
- Planning to undergo or has undergone a surgical resection for suspected adenocarcinoma of the colon or rectum with curative intent.
- 18 years old or older
- Willing and able to provide informed consent
- Willing to have additional blood samples collected during routine surveillance visits
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (20)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| ThedaCare Regional Cancer Center Coordinator of this site? Confirm its status | Appleton | United States | Recruiting |
| The Center for Cancer and Blood Disorders Coordinator of this site? Confirm its status | Bethesda | United States | Recruiting |
| Aultman Hospital Coordinator of this site? Confirm its status | Canton | United States | Recruiting |
| TriHealth Cancer Institute Coordinator of this site? Confirm its status | Cincinnati | United States | Recruiting |
| Ohio State University Coordinator of this site? Confirm its status | Columbus | United States | Recruiting |
| OhioHealth Research Institute Coordinator of this site? Confirm its status | Columbus | United States | Recruiting |
| Mercy Clinic Oncology - Fort Smith Coordinator of this site? Confirm its status | Fort Smith | United States | Recruiting |
| MemorialCare Coordinator of this site? Confirm its status | Fountain Valley | United States | Recruiting |
| Southeastern Medical Oncology Center Coordinator of this site? Confirm its status | Goldsboro | United States | Recruiting |
| Mercy Clinic Oncology and Hematology - Joplin Coordinator of this site? Confirm its status | Joplin | United States | Recruiting |
| Mercy Clinic Oncology and Hematology - Coletta Coordinator of this site? Confirm its status | Oklahoma City | United States | Recruiting |
| Nebraska Cancer Specialists Coordinator of this site? Confirm its status | Omaha | United States | Recruiting |
| Utah Cancer Specialists Coordinator of this site? Confirm its status | Salt Lake City | United States | Recruiting |
| University of Washington Fred Hutchinson Cancer Center Coordinator of this site? Confirm its status | Seattle | United States | Recruiting |
| Mercy Clinic Cancer and Hematology - Chub O'Reilly Cancer Center Coordinator of this site? Confirm its status | Springfield | United States | Recruiting |
| Mercy Clinic Oncology and Hematology Sindelar Cancer Center Coordinator of this site? Confirm its status | St Louis | United States | Recruiting |
| Washington University School of Medicine Coordinator of this site? Confirm its status | St Louis | United States | Recruiting |
| Mercy Clinic Oncology and Hematology - David C. Pratt Cancer Center Coordinator of this site? Confirm its status | St Louis | United States | Recruiting |
| Toledo Clinic Cancer Center Coordinator of this site? Confirm its status | Toledo | United States | Recruiting |
| Cancer Care Associates of York Coordinator of this site? Confirm its status | York | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.