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NCT05243485Completed

Prehospital Triage of Patients With Suspected Non-ST-segment Elevation Acute Coronary Syndrome: the TRIAGE-ACS Study

Source: ClinicalTrials.gov · Last updated 12 Feb 2024

Brief summary (registry, in English)

With the Emergency Medical Services (EMS), no prehospital risk stratification and triage is performed for patients suspected of having an Non-ST-segment elevation Acute Coronary Syndrome (NSTE-ACS). While the latest ESC Guidelines recommend an early invasive strategy within 24 hours for all high risk NSTE-ACS patients and same-day transfer to a PCI (Percutaneous Coronary Intervention) center. With the potential emerging logistical problem surrounding this, prehospital risk stratification and triage can have great benefits in this population as well, especially in patients with a high risk of having an NSTE-ACS. The recently validated PreHEART score makes it possible to stratify patients in a low-risk and high-risk group for having a NSTE-ACS and gives the EMS the opportunity to make triage decisions in the prehospital setting. Patients with a high risk for having an NSTE-ACS are transferred directly to an PCI-center for further diagnostic work-up. Patients with a low risk for having NSTE-ACS and transferred to the ED of the nearest hospital without PCI facilities (non-PCI center) for further diagnostic work-up, resulting in an optimization of the regional care utilization. This is the first study to focus on patients who are at a high risk of having an NSTE-ACS and to assess if whether prehospital triage using the PreHEART score is able to significantly reduce time to final invasive diagnostics and revascularization in patients in need of coronary revascularization.

Status (registry)
Completed
Study type
Observational
Enrollment
1071 (actual)
First submitted
26 Jan 2022
Start date
1 Apr 2021
Primary completion date
19 Dec 2022
Lead sponsor
Catharina Ziekenhuis Eindhoven
NCT number
NCT05243485

What you commit to

  • Study type: Observational
  • Participants enrolled: 1071
  • From 1 Apr 2021 to the primary completion date, 19 Dec 2022
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • ST-segment elevation Acute Coronary Syndrome

Other

  • Post resuscitation patients
  • Hemodynamic instability defined as Killip Class IV
  • Suspected other life treating pathology
  • Pregnancy
  • No informed consent for data usage

Who the study is looking for

  • Chest pain suspected for NSTE-ACS
  • Age ≥ 18 years
  • Intention to transfer patient to Emergency Department

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Catharina hospital
Coordinator of this site? Confirm its status
EindhovenNetherlandsUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.