NCT05246345Recruiting
Venetoclax Resistance Landscape in Chronic Lymphocytic Leukemia
Source: ClinicalTrials.gov · Last updated 9 Jan 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The purpose of this study is to collect medical informations and samples from refractory and/or relapsed chronic lymphocytic leukemia during or after venetoclax treatment, in order to evaluate the frequency of resistance mechanisms.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 50 (estimated)
- First submitted
- 13 Oct 2021
- Start date
- 7 Mar 2022
- Primary completion date
- Mar 2027
- Lead sponsor
- University Hospital, Clermont-Ferrand
- Diseases
- Chronic lymphocytic leukaemia
- NCT number
- NCT05246345
What you commit to
- Study type: Observational
- Planned participants: 50
- From 7 Mar 2022 to the primary completion date, Mar 2027
- 14 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Patients of their legal guardians refusing to participate
- \-
Who the study is looking for
- Age greater than or equal to 18 years old;
- chronic lymphocytic leukemia diagnosis according to iwCLL criteria;
- refractory and/or relapsed disease during or after venetoclax treatment;
- tumor samples available.
- Relapse might be progressive chronic lymphocytic leukemia or transformation into Richter syndrome.
- Patients must be able to express their opposition to be enrolled in this study, if need be.
- Patients must be affiliated at the French Social Security system
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (14)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHU D'amiens Coordinator of this site? Confirm its status | Amiens | France | Not yet recruiting |
| CHU de Besançon Coordinator of this site? Confirm its status | Besançon | France | Not yet recruiting |
| Hopital Avicenne Coordinator of this site? Confirm its status | Bobigny | France | Not yet recruiting |
| CHU de Clermont-Ferrand Coordinator of this site? Confirm its status | Clermont-Ferrand | France | Not yet recruiting |
| CHU Clermont-Ferrand Coordinator of this site? Confirm its status | Clermont-Ferrand | France | Not yet recruiting |
| Chu Grenoble Coordinator of this site? Confirm its status | Grenoble | France | Not yet recruiting |
| CHRU de Lille Coordinator of this site? Confirm its status | Lille | France | Not yet recruiting |
| Centre Leon Berard Coordinator of this site? Confirm its status | Lyon | France | Not yet recruiting |
| CHU de Montpellier Coordinator of this site? Confirm its status | Montpellier | France | Not yet recruiting |
| CHU Nancy Coordinator of this site? Confirm its status | Nancy | France | Not yet recruiting |
| Hopital Pitie-Salpetriere Coordinator of this site? Confirm its status | Paris | France | Not yet recruiting |
| Hopital Haut-Leveque Coordinator of this site? Confirm its status | Pessac | France | Not yet recruiting |
| CHU de Reims Coordinator of this site? Confirm its status | Reims | France | Recruiting |
| IUCT Oncopôle Coordinator of this site? Confirm its status | Toulouse | France | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.