NCT05247424CompletedPhase 4
Pretreatment With Unfractionated Heparin for ST Elevation Myocardial Infarction
Source: ClinicalTrials.gov · Last updated 1 May 2025
Brief summary (registry, in English)
Rupture of a coronary artery plaque leads to thrombotic occlusion of the coronary artery and would present as ST segment elevation myocardial infarction. Early treatment with aspirin and early primary percutaneous coronary intervention are indicated. Anticoagulation therapy, usually with unfractionated heparin, is required during percutaneous coronary intervention. Investigators hypothesis is that pretreatment with unfractionated heparin in addition to aspirin at first medical contact may facilitate spontaneous reperfusion of culprit artery and procedural thrombotic complication in patients with ST elevation myocardial infarction without significant risk of bleeding complications.
- Status (registry)
- Completed
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 600 (actual)
- First submitted
- 30 Jan 2022
- Start date
- 10 Mar 2022
- Primary completion date
- 5 Feb 2025
- Lead sponsor
- University Medical Centre Ljubljana
- Diseases
- Coronary artery disease
- NCT number
- NCT05247424
What you commit to
- Study type: Interventional · Phase 4
- Participants enrolled: 600
- From 10 Mar 2022 to the primary completion date, 5 Feb 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Cardiac arrest before randomization
Other
- Pregnancy
- Cardiogenic shock at presentation (hemodynamic instability)
- Duration of symptoms for more than 6 hours before presentation
Who the study is looking for
- Adult patients with STEMI referred for primary PCI
- Duration of symptoms less than 6 hours before presentation
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| UMC Ljubljana Coordinator of this site? Confirm its status | Ljubljana | Slovenia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.