NCT05252195Active, not recruiting
Optimizing Detection and Prediction of Changes in Cognitive Function in Multiple Sclerosis (MS)
Optimizing Detection and Prediction of Changes in Cognitive Function in Multiple Sclerosis
Source: ClinicalTrials.gov · Last updated 27 Apr 2025
Brief summary (registry, in English)
The researchers will use technology-assisted ambulatory assessment techniques to examine cognitive dysfunction in people with Multiple Sclerosis (MS). The researchers will determine if ambulatory assessments are sensitive to subtle declines in cognitive functioning. They will also explore the impact of modifiable factors, such as sleep, physical activity, mood, and somatic symptoms on cognitive function. These efforts will uncover behavioral and medical intervention methods. Finally, they will explore whether variability in cognitive functioning predicts short- and long-term changes in other patient-centered functional domains, social participation and physical functioning.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 300 (actual)
- First submitted
- 12 Feb 2022
- Start date
- 24 May 2022
- Primary completion date
- Mar 2027
- Lead sponsor
- University of Michigan
- Diseases
- Multiple sclerosis
- NCT number
- NCT05252195
What you commit to
- Study type: Observational
- Participants enrolled: 300
- From 24 May 2022 to the primary completion date, Mar 2027
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- MS relapse within the past 30 days (may become eligible after 30 days; criteria used at T1, T2, and T3).
- Inability to use study data collection tools (i.e., ActiGraph wrist-worn activity watch, smart phone app).
Who the study is looking for
- Are able to fluently converse and read in English.
- Multiple Sclerosis (MS) diagnosis (confirmed from neurologist, all relapsing and progressive subtypes included)
- Ambulate either independently or with the use of a cane or walker (or similar device) for at least 50% of the time at baseline
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Michigan Coordinator of this site? Confirm its status | Ann Arbor | United States | Unknown status |
| Wayne State University Coordinator of this site? Confirm its status | Detroit | United States | Unknown status |
| University of Washington Coordinator of this site? Confirm its status | Seattle | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.