NCT05254431Recruiting
The Effect of Interval Exercise on Functional Outcomes in Veterans With COPD and OSA
Source: ClinicalTrials.gov · Last updated 24 Apr 2026
Brief summary (registry, in English)
The term "Overlap Syndrome" (OS) is used to describe the presence of both chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) in a single patient. Due to premature aging, patients with OS are prone to developing functional decline up to 20 years earlier than the general population. The International Classification of Functioning, Disability and Health (ICF) evaluates functional status in chronic pulmonary disease globally in 5 domains. The investigators propose to study validated outcomes in 3 of these domains: 1) participation in life situations; 2) physical activity; and 3) cardiovascular health. The investigators long-term goal is to develop an exercise strategy tailored to Veterans with OS which will reduce the risk of functional decline through increased PA.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 28 (estimated)
- First submitted
- 28 Jan 2022
- Start date
- 1 Apr 2022
- Primary completion date
- 1 Apr 2027
- Lead sponsor
- VA Office of Research and Development
- Diseases
- COPD
- NCT number
- NCT05254431
What you commit to
- Study type: Interventional
- Planned participants: 28
- From 1 Apr 2022 to the primary completion date, 1 Apr 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- CAD, as defined by anyone of the following: history of CABG, prior positive stress test for ischemia, infarction or angina or medical problem
- Fall risk, defined as more than 2 falls in the prior month
- Hospitalization in prior month
- Daytime home oxygen 6. Participation in structured exercise, defined by the Physical Activity Scale for the Elderly (PASE) as more than 1 hour of activity spent in moderate activity and any strenuous activity performed over prior 7 days.
Other
- Orthopedic problems as defined by joint pain limiting ambulation
Who the study is looking for
- Diagnosis of COPD and OSA, i.e., Overlap Syndrome Diagnosis of Overlap Syndrome (both COPD and OSA), confirmed in CPRS from spirometry or pulmonary function test of FEV1/FVC \<70 for COPD and a polysomnogram or home-based study for OSA.
- Montreal Cognitive Assessment (MoCA) \>20
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Salem VA Medical Center, Salem, VA Coordinator of this site? Confirm its status | Salem | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.