NCT05255172Enrolling by invitation
Exercise Intervention in Patients With Heart Failure With Preserved and Reduced Ejection Fraction
Physiological Mechanisms Affecting Exercise Capacity in Patients With Heart Failure - an Exercise Intervention Study Evaluated With Several Modalities
Source: ClinicalTrials.gov · Last updated 29 Jun 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The objective of this study is to assess by what physiological mechanisms patients with heart failure benefit from exercise. Effects of an exercise intervention will be assessed for both central (heart and lungs) and peripheral (muscle fiber and mitochondria) factors.
- Status (registry)
- Enrolling by invitation
- Study type
- Interventional
- Enrollment
- 120 (estimated)
- First submitted
- 20 Jan 2022
- Start date
- Jun 2022
- Primary completion date
- Aug 2027
- Lead sponsor
- Region Skane
- Diseases
- Heart failure
- NCT number
- NCT05255172
What you commit to
- Study type: Interventional
- Planned participants: 120
- From Jun 2022 to the primary completion date, Aug 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Devices or implants not compatible with magnetic resonance imaging or exercise testing
Other illness
- Currently or within the past 6 months been involved in cardiac rehab with exercise
- Any orthopedic or medical condition affecting participation in testing and training
- Moderate or severe valvular disease
- Moderate or severe chronic obstructive pulmonary disease
Other
- Signs of acute ischemia during baseline cardiopulmonary exercise testing
- Participation in other clinical trials that may affect results
- Atrial fibrillation
- NYHA class IV
Who the study is looking for
- Signs and symptoms of heart failure
- Age ≥50 years
- Stable chronic heart failure (no hospitalizations within past month, no new medications past month)
- Able to understand and follow exercise prescription
- Currently physically inactive (less than 150 minutes/week moderate intensity exercise)
Age in the registry: 50 years to 90 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Skåne University Hospital Lund Coordinator of this site? Confirm its status | Lund | Sweden | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.