NCT05270759Completed
Non-invasive Assessment to Predict Tolerance to Fluid Removal on Intermittent Kidney Replacement Therapy
Source: ClinicalTrials.gov · Last updated 19 Sept 2024
Brief summary (registry, in English)
This prospective cohort study aim to investigate the ability of multiple types of assessments including 1) the modified Venous Excess Ultrasound (VExUS) assessment, 2) non-invasive estimation of absolute blood volume (ABV), and 3) change in carotid Doppler at the start of IKRT to predict IDHE in acutely ill hospitalized patients. The secondary aim will be to determine whether each modality improves the prediction of IHDE compared to the evaluation of the attending physician and whether they also predict cerebral hypoxia during IKRT measured by near-infrared spectroscopy (NIRS). Finally, detailed hemodynamic data including relative blood volume monitoring, tissue oximetry, and other parameters will be collected continuously during IKRT sessions enabling exploratory analyses aimed at identifying hemodynamic phenotypes related to IDHE during IKRT.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 93 (actual)
- First submitted
- 26 Feb 2022
- Start date
- 1 Mar 2022
- Primary completion date
- 20 Aug 2024
- Lead sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
- Diseases
- Chronic kidney disease
- NCT number
- NCT05270759
What you commit to
- Study type: Observational
- Participants enrolled: 93
- From 1 Mar 2022 to the primary completion date, 20 Aug 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Planned hospital discharge, death, or transition to comfort care within 48 hours according to the attending physician
- End of active care (awaiting hospital discharge)
Who the study is looking for
- Adult patient ≥18 year-old
- Hospitalized at the CHUM in the intensive care unit (ICU) or general ward
- Receiving or planned ≥3x/week IKRT treatments
- Planned on-line hemodiafiltration (HDF) or hemodialysis (HD) sessions with ≥1L of fluid removal per session
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Centre Hospitalier de l'Université de Montréal Coordinator of this site? Confirm its status | Montreal | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.