NCT05273996Active, not recruitingPhase 4
Predictors of Cognitive Outcomes in Geriatric Depression
Phenotype Predictors of Cognitive Outcomes in Geriatric Depression
Source: ClinicalTrials.gov · Last updated 22 May 2026
Brief summary (registry, in English)
This study will focus on examining effects of stress on long-term mood and cognitive outcomes of late-life depression. It will also example the neural underpinnings of these changes using structural and functional brain imaging. Understanding how effects of stress in older depressed adults, as well as factors that might minimize those effects, lead to particular mood and cognitive outcomes will inform future development of novel prevention strategies.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 75 (estimated)
- First submitted
- 13 Dec 2021
- Start date
- 28 Sept 2021
- Primary completion date
- 30 Apr 2027
- Lead sponsor
- David Steffens
- Diseases
- Depression
- NCT number
- NCT05273996
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 75
- From 28 Sept 2021 to the primary completion date, 30 Apr 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- lifetime alcohol/drug dependence
Other illness
- conditions associated with brain abnormalities such hydrocephalus, benign and cancerous brain tumors, epilepsy, Parkinson's disease, Huntington's chorea, dementia, demyelinating diseases, etc.
- untreated endocrine disorder other than diabetes mellitus
- established clinical diagnosis of dementia
- other primary psychiatric disorders, e.g., panic disorder, social phobia, obsessive- compulsive disorder, schizoaffective disorder, schizophrenia, bipolar disorder
Who the study is looking for
- major depression, single episode or recurrent;
- ability to read and write English;
- Mini-Mental State Examination \>25.
Age in the registry: 65 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| UConn Health Coordinator of this site? Confirm its status | Farmington | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.