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NCT05275842Completed

CPT-L to Improve Outcomes for Individuals With HIV and PTSD

Development and Feasibility Testing of an Integrated PTSD and Adherence Intervention Cognitive Processing Therapy-Lifesteps (CPT-L) to Improve HIV Outcomes

Source: ClinicalTrials.gov · Last updated 4 Mar 2025

Brief summary (registry, in English)

This study plans to adapt and examine the acceptability and feasibility of an evidence-based PTSD treatment that has reduced other HIV transmission behavior (e.g., sexual risk), Cognitive Processing Therapy (CPT), at an HIV clinic as a strategy to improve HIV outcomes in this population.

Status (registry)
Completed
Study type
Interventional
Enrollment
41 (actual)
First submitted
25 Feb 2022
Start date
13 Jul 2022
Primary completion date
30 Aug 2024
Lead sponsor
Medical University of South Carolina
Diseases
HIV
NCT number
NCT05275842

What you commit to

  • Study type: Interventional
  • Participants enrolled: 41
  • From 13 Jul 2022 to the primary completion date, 30 Aug 2024
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study design.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Evidence of significant cognitive impairment as assessed by the Montreal Cognitive Assessment Test (MoCA; in the severe range).
  • Evidence of developmental delays, or pervasive developmental disorder, or active suicidal or homicidal ideations.

Other

  • Evidence of psychotic symptoms (e.g., active hallucinations, delusions, impaired thought processes).

Who the study is looking for

  • Individuals that are 18 years and older
  • Linked with and/or eligible for treatment at a Ryan White clinic in South Carolina.
  • Participant meets clinically significant threshold of DSM-V PTSD criteria as determined by a Clinician Administered PTSD Scale for DSM-5 (CAPS-5) clinical interview.
  • No changes in psychotropic medication within 4 weeks of study enrollment.
  • Able to speak, read, and write English.
  • Meet at least one of the following HIV care criteria:
    • Diagnosed with HIV in the last 3 months;
    • Detectable viral load in the last 12 months;
    • Failed to show up for or missed 1 or more HIV care appointments in the past 12 months;
    • Last HIV care visit was more than 6 months ago;
    • Self-reporting less than 90% ART adherence in the past 4 weeks.
  • A score of at least 10 on the Montreal Cognitive Assessment test (MoCA)

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
Medical University of South Carolina
Coordinator of this site? Confirm its status		CharlestonUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.