NCT05277025Recruiting
Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes
Source: ClinicalTrials.gov · Last updated 19 Aug 2026
Brief summary (registry, in English)
Fibromyalgia (FM) is a chronic musculoskeletal pain disorder that afflicts up to 4% of the general population. The evaluation of pain mechanisms in FM has shown predominant central abnormalities and therefore has been designated as nociplastic pain syndrome. Rheumatoid arthritis (RA) is characterized by polyarthritis and pain from inflamed tissues, consistent with nociceptive pain. FM and RA patients may utilize overlapping pain mechanisms resulting in nociceptive and nociplastic pain.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 150 (estimated)
- First submitted
- 28 Feb 2022
- Start date
- 22 Mar 2022
- Primary completion date
- 28 Jul 2027
- Lead sponsor
- University of Florida
- Diseases
- Rheumatoid arthritis
- NCT number
- NCT05277025
What you commit to
- Study type: Observational
- Planned participants: 150
- From 22 Mar 2022 to the primary completion date, 28 Jul 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Diabetes
- Cancer
- Advanced liver, kidney or cardiovascular disease
Other
- Neuropathic pain
Who the study is looking for
- Ages 18-70
- Fulfills the 1990 and 2011 American College of Rheumatology Criteria for FM
- Fulfills the 2010 ACR-EULAR classification criteria for RA
- Healthy volunteers: No significant pain/fatigue/depression/anxiety.
Age in the registry: 18 years to 70 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Florida Coordinator of this site? Confirm its status | Gainesville | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.