Fact CheckerSign in

NCT05277025Recruiting

Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes

Source: ClinicalTrials.gov · Last updated 19 Aug 2026

Brief summary (registry, in English)

Fibromyalgia (FM) is a chronic musculoskeletal pain disorder that afflicts up to 4% of the general population. The evaluation of pain mechanisms in FM has shown predominant central abnormalities and therefore has been designated as nociplastic pain syndrome. Rheumatoid arthritis (RA) is characterized by polyarthritis and pain from inflamed tissues, consistent with nociceptive pain. FM and RA patients may utilize overlapping pain mechanisms resulting in nociceptive and nociplastic pain.

Status (registry)
Recruiting
Study type
Observational
Enrollment
150 (estimated)
First submitted
28 Feb 2022
Start date
22 Mar 2022
Primary completion date
28 Jul 2027
Lead sponsor
University of Florida
NCT number
NCT05277025

What you commit to

  • Study type: Observational
  • Planned participants: 150
  • From 22 Mar 2022 to the primary completion date, 28 Jul 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Diabetes
  • Cancer
  • Advanced liver, kidney or cardiovascular disease

Other

  • Neuropathic pain

Who the study is looking for

  • Ages 18-70
  • Fulfills the 1990 and 2011 American College of Rheumatology Criteria for FM
  • Fulfills the 2010 ACR-EULAR classification criteria for RA
  • Healthy volunteers: No significant pain/fatigue/depression/anxiety.

Age in the registry: 18 years to 70 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
University of Florida
Coordinator of this site? Confirm its status
GainesvilleUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.