NCT05277714Recruiting
Neurofeedback Based on Near-infrared Spectroscopy as a Therapy for Food Addiction in Obese Subjects.
Source: ClinicalTrials.gov · Last updated 8 Aug 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The hypothesis is that the increase in dlPFC brain activity via near-infrared spectroscopy-based Neurofeedback (fNIRS-based NF) training based on near-infrared spectroscopy would allow an improvement of the eating behavior, thus promoting a long-term weight loss in obese subjects. Patients will be trained during a month with 8 NF sessions and results based on clinical data and different questionnaires results will be compared between inclusion and 3 months later
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 50 (estimated)
- First submitted
- 2 Mar 2022
- Start date
- 25 May 2022
- Primary completion date
- May 2026
- Lead sponsor
- Rennes University Hospital
- Diseases
- Obesity
- NCT number
- NCT05277714
What you commit to
- Study type: Interventional
- Planned participants: 50
- From 25 May 2022 to the primary completion date, May 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Psychotropic drugs, except antidepressants stabilized for at least 3 weeks and benzodiazepines
Other illness
- Psychotic psychiatric disorders (schizophrenic disorders and bipolar disorders);
- History of bariatric surgery;
Age
- Persons of legal age under legal protection (safeguard of justice, curatorship, guardianship), persons deprived of liberty.
Other
- Addiction to alcohol or other psychoactive substances (except tobacco);
- Current treatment in the nutrition unit;
- Insufficient command of French;
- Pregnant or breast-feeding woman;
- Contraindications to fMRI
- Inability to perform the fNIRS procedure due to blockage or attenuation of the light at the capillary level
Who the study is looking for
- Eligible for obesity surgery according to the 2009 French High Authority on Health (HAS) criteria (BMI ≥40 or BMI ≥35 with comorbidities)
- Right-handed
- Presenting a food addiction determined by the YFAS 2.0 questionnaire ;
- Affiliated to a social security system;
- Having given free and informed consent in writing.
Age in the registry: 18 years to 55 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHU Rennes Coordinator of this site? Confirm its status | Rennes | France | Recruiting |
Related publications
- Neurofeedback intervention based on functional near-infrared spectroscopy compared with sham control to improve inhibitory cognitive control in patients with severe obesity and food addiction: The protocol of a monocentric prospective randomized parallel-group single-blind interventional study.Clin Nutr ESPEN · 2026 · PMID 42435898
This page is information, not medical advice. Discuss any trial with your doctor.