NCT05280730Completed
Assessment of Neurodevelopmental Needs in Duchenne Muscular Dystrophy
Source: ClinicalTrials.gov · Last updated 14 Aug 2025
Brief summary (registry, in English)
Duchenne Muscular Dystrophy is a genetic disease that causes progressive muscle weakness. There is now substantial evidence that boys with this disease do not demonstrate age-related gains in their cognitive skills. The goals of this study are (i) to use a technology-enabled neurobehavioral assessment called National Institutes of Health Toolbox Cognition Battery (NIHTB-CB) to assess brain development over time; (ii) engage with key-stakeholders to understand how neurodevelopmental problems like attention-deficit hyperactivity, autism spectrum affects individuals (and/or) families, so that we can understand meaningful effects of a potential treatment at an individual level, and (iii) to investigate using brain magnetic resonance imaging (MRI) changes in brain connectivity.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 50 (actual)
- First submitted
- 4 Mar 2022
- Start date
- 2 Feb 2022
- Primary completion date
- 30 Sept 2024
- Lead sponsor
- Virginia Commonwealth University
- Diseases
- Duchenne muscular dystrophy
- NCT number
- NCT05280730
What you commit to
- Study type: Observational
- Participants enrolled: 50
- From 2 Feb 2022 to the primary completion date, 30 Sept 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- For MRI, braces or any metal implants.
Other
- Care-giver unable to give consent
- Any handicap that does not allow the ability to use an IPAD
Who the study is looking for
- Boys with confirmed genetic mutation in the dystrophin gene
- Boys with clinical features of DMD and in whom muscle biopsy showed absence of dystrophin
- Boys with clinical features of DMD and in whom there is a family history of DMD
- Symptomatic carrier girls with DMD
- Ages 3 and above at time of study screening
Age in the registry: 3 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Children's Hospital of Richmond Coordinator of this site? Confirm its status | Richmond | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.