NCT05283473Completed
Serum Magnesium Concentration in Magnesium Sulfate Therapy for Severe Preeclampsia
Serum Concentration of Magnesium Attained in Magnesium Sulfate Therapy in Pregnant Women With Severe Preeclampsia
Source: ClinicalTrials.gov · Last updated 7 Jan 2025
Brief summary (registry, in English)
Pregnant women diagnosed with pre-eclampsia with severe features will be treated with magnesium sulfate to prevent seizures. Magnesium sulfate will be administered according to My Duc Hospital's protocol for treatment of pre-eclampsia (a loading dose of 4.5g given intravenously in 20 min, followed by a maintenance dose at an infusion rate of 1.5g/h). Serum magnesium concentrations will be measured before the loading dose and 0.5h, 1h, 2h, and every 6 hours thereafter.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 64 (actual)
- First submitted
- 12 Feb 2022
- Start date
- 15 Mar 2022
- Primary completion date
- 21 Feb 2024
- Lead sponsor
- Mỹ Đức Hospital
- NCT number
- NCT05283473
What you commit to
- Study type: Observational
- Participants enrolled: 64
- From 15 Mar 2022 to the primary completion date, 21 Feb 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Known hypersensitivity to the drug,
Lab values
- Impaired renal function (eGFR \< 60 mL/min/ 1,73 m2 or oliguria )
- Occurrence of eclampsia before magnesium sulfate administration
Other
- Severe myasthenia, atrioventricular block
- A diminished level of consciousness.
Who the study is looking for
- Pregnant women
- Aged ≥ 18
- Diagnosed with pre-eclampsia with severe features, with or without chronic hypertension, as defined by the American College of Obstetricians and Gynecologists (ACOG) diagnosis criteria.
- Provision of written informed consent to participate as shown by a signature on the patient consent form.
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| My Duc Hospital Coordinator of this site? Confirm its status | Ho Chi Minh City | Vietnam | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.