NCT05283577Active, not recruiting
Electroacupuncture for the Management of Symptom Clusters in Cancer Patients and Survivors
Electroacupuncture for the Management of Symptom Clusters in Cancer Patients and Survivors (EAST): A Feasibility Study
Source: ClinicalTrials.gov · Last updated 27 Oct 2026
Brief summary (registry, in English)
This is a sham-controlled, patient and assessor-blinded pilot trial to evaluate the feasibility of administering EA as an intervention for symptom clusters in cancer patients and survivors, and to evaluate the degree that EA could reduce symptom clusters and the possible underlying mechanisms through examining its influence on biomarkers that are linked with the symptoms. Participants will be randomized to either the treatment arm (those who will receive EA) or the control arm (those who will receive sham-EA). The treatment period for both groups will be 10 weeks. There will be one study visit a week over the course of the 10-week treatment period, for a total of 10 study treatment visits. Participants in the treatment arm will receive EA at 13 standardized acu-points that have been chosen for their therapeutic effects. Participants in the control arm will receive electrical stimulation at non-disease acu-points. There will be four data collection time points for each participant: (1) baseline, (2) mid-treatment (5 weeks from baseline), (3) end of treatment (10 weeks from baseline), and (4) 4 weeks after end of treatment (14 weeks from baseline). At each of these timepoints, 10mL of peripheral blood will be collected for a biomarker analysis and participants will be asked to complete 4 questionnaires and a computerized cognitive test to evaluate their cognitive function, fatigue level, insomnia, psychological distress, and quality of life. An optional neuroimaging procedure will be available to all eligible participants. In total, study participation will last for 14 weeks.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 70 (actual)
- First submitted
- 3 Feb 2022
- Start date
- 15 Apr 2022
- Primary completion date
- Dec 2026
- Lead sponsor
- University of California, Irvine
- Diseases
- Childhood cancers
- NCT number
- NCT05283577
What you commit to
- Study type: Interventional
- Participants enrolled: 70
- From 15 Apr 2022 to the primary completion date, Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Has pacemaker or other electronic metal implants
- Already receiving acupuncture therapy or received acupuncture treatment in the past 3 months.
- Breastfeeding, pregnant or are planning get pregnant during the study period
- Additional exclusion criteria for optional neuroimaging procedure:
- \- Has any contraindications to fMRI including metal fragments/implants in the body, sever claustrophobia, and non-removable metal orthodontic braces, metallic retainers and oral wires.
Other illness
- Severe psychiatric or medical disorders which would affect cognitive assessments
- Known bleeding disorder (e.g. hemophilia, Von Willebrand's disease, thrombocytopenia)
- Epilepsy
Other
- Presence of metastasis
- Severe needle phobia
Who the study is looking for
- Patients diagnosed with cancer that have received anti-cancer treatment
- 16 years of age or older
- Life expectancy ≥ 6 months
- Complaints of one or more of the following symptoms: memory impairment/attention deficit, fatigue, insomnia, depression, or anxiety over the past 7 days
Age in the registry: 16 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| UCI Health Susan Samueli Integrative Health Institute Coordinator of this site? Confirm its status | Irvine | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.