NCT05291104Completed
Dietary Allowance of Methyl Donor Nutrients to Minimize Risks of Non-alcoholic Fatty Liver Progression
Dietary Allowance of Methyl Donor Nutrients to Minimize Risks of Non-alcoholic Fatty Liver Progression: Novel Diagnostic and Therapeutic Markers in Metabolomics of Gut Microbiome/Host Methyl Nutrition and the Working Mechanisms
Source: ClinicalTrials.gov · Last updated 14 Apr 2026
Brief summary (registry, in English)
Investigate the methyl donors requirement of NAFLD patients to correct the malnutrition, lipid-toxicity, microbiota dysfunction, and metabolomics biomarkers.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 51 (actual)
- First submitted
- 10 Mar 2022
- Start date
- 25 Apr 2022
- Primary completion date
- 31 Jul 2024
- Lead sponsor
- Fu Jen Catholic University Hospital
- Diseases
- Fatty liver disease (MASLD/MASH)
- NCT number
- NCT05291104
What you commit to
- Study type: Interventional
- Participants enrolled: 51
- From 25 Apr 2022 to the primary completion date, 31 Jul 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Taking drugs that causes fatty liver
Other illness
- Asymptomatic carrier of hepatitis B and C
- Liver disease except NAFLD
- Cancer except liver cancer
- Heart disease, vascular disease, or psychosis
Other
- Inflammation about stomach or intestines
- Pregnancy
- Intake alcohol over 100 g or unaccessible intake alcohol
Who the study is looking for
- NAFLD/NASH patients
- Folate levels in plasma \< 6 ng/mL or choline levels in plasma \< 5 micromol per liter
- Folate intake \< estimated average requirement or choline intake \< 50% adequate Intakes
- Homocysteine levels in plasma \> 9 micromol per liter
Age in the registry: 20 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Taipei Hospital, Ministry of Health and Welfare Coordinator of this site? Confirm its status | New Taipei City | Taiwan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.