NCT05292183Completed
Modulation of Emotion Perception in Humans Via Amygdala Stimulation
Neuromodulation of Affective Valence in Humans by Amygdala Stimulation
Source: ClinicalTrials.gov · Last updated 22 Sept 2025
Brief summary (registry, in English)
This study will enroll patients with epilepsy who are being evaluated for epilepsy surgery and have intracranial EEG electrodes. In this study, the aim is to record brain signals from areas important in social and emotional processing and to understand how electrical brain stimulation - called neuromodulation - affects such processing. Patients enrolled in this study will be asked to view images depicting a variety of emotionally positive, negative, or neutral themes. As the patient views these images, a small amount of imperceptible and painless electric current will be used to map function of certain parts of a human brain. The overarching goal of the study is to determine if neuromodulation can be used in certain areas of the brain to treat cognitive disorders such as memory loss and post-traumatic stress disorder.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 16 (actual)
- First submitted
- 14 Mar 2022
- Start date
- 31 Mar 2022
- Primary completion date
- 16 Feb 2024
- Lead sponsor
- Dartmouth-Hitchcock Medical Center
- Diseases
- Epilepsy
- NCT number
- NCT05292183
What you commit to
- Study type: Interventional
- Participants enrolled: 16
- From 31 Mar 2022 to the primary completion date, 16 Feb 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Additional neurological disorders (such as dementia, stroke, brain tumor, etc.)
- Any psychiatric condition that would limit their ability to provide consent and/or perform study tasks within normal limits. This would be based on presurgical psychiatric assessment.
Other
- Anything else, that in the opinion of the principal investigator, might preclude them from participating in the study
Who the study is looking for
- Age of 18 years or older
- FSIQ 75 and above or any equivalent test of generalized intelligence as determined by the PI to adequately predict engagement in the task
- Able to give independent consent for participation in the study
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Dartmouth Hitchcock Medical Center Coordinator of this site? Confirm its status | Lebanon | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.