NCT05295615Recruiting
Pulsed Electromagnetic Field Treatment In Patients With Alzheimer's Disease
Effects of PEMF Treatment on Patients With Mild to Moderate Alzheimer's Disease in a Controlled Pilot Study
Source: ClinicalTrials.gov · Last updated 17 Sept 2026
Brief summary (registry, in English)
An open label pilot study in mild to moderate AD patients to assess the effects of treatment with ECHS AD pulsed electromagnetic treatment device on disease progression. Enrolled patients will receive active devices. They will treat themselves at home three times a day for 15 minutes over 120 days. Primary end points are the The Alzheimer's Disease Assessment Scale-Cognitive Subscale and the Mini-Mental State Exam. Participants will be followed-up for 9 months post-treatment.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 15 Feb 2022
- Start date
- 1 May 2023
- Primary completion date
- 30 Jun 2027
- Lead sponsor
- Herrick Medical LLC
- Diseases
- Alzheimer disease
- NCT number
- NCT05295615
What you commit to
- Study type: Interventional
- Planned participants: 40
- From 1 May 2023 to the primary completion date, 30 Jun 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Currently taking medication that lowers the seizure threshold
- Major surgery (defined as any major abdominal, vascular or thoracic surgery requiring general anesthesia and resulting in a period of \>1 week hospitalization) within 4 weeks
- Participation in another clinical trial within the previous 30 days
- Metal implants in the head, (i.e., cochlear implants, implanted brain stimulators and neurostimulators, aneurysm clips) with the exception of metal implants in mouth
Other illness
- History of epileptic seizures or epilepsy
- Presence of depression, bipolar disorder, a psychotic disorder, or any other neurological or psychiatric condition (whether now or in the past), which the Investigator finds as interfering with the study
- Alcoholism or substance use disorder as defined by Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) within last 5 years (addicted more than one year and or in remission less than 3 years) or severe sleep deprivation
Other
- The patient lacks capacity to consent to study participation and no surrogate is available to provide consent
- Severe agitation that would interfere with study procedures
- Head anatomy that interferes with the fit of the treatment device
Who the study is looking for
- Age ≥ 50 years
- Patients diagnosed with mild to moderate Alzheimer's Dementia defi
- At least an eighth grade of educational achievement
- If female, post-menopausal.
- MMSE score between 16 and 26
- Capable of providing consent or having a surrogate (e.g., spouse, family member) capable of providing consent if participant lacks consent capacity
- Able and willing to comply with the protocol
- If the participant is receiving a cholinesterase inhibitor and/or memantine, such medication has been prescribed for at least 3 months prior to screening and the dose is stable for at least 60 days prior to screening (that dose needs to be maintained throughout the period of this study)
- Spouse, family member or professional caregiver agree and are capable of taking care of the participation of the patient in the study (answering questions regarding the patient's condition, assuming responsibility for medication, and applying and supervising the daily PEMF treatments)
- Physical clearance for study participation as evaluated by the clinician
Age in the registry: 50 years to 100 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hackensack Medical Center Coordinator of this site? Confirm its status | Hackensack | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.