NCT05295953Completed
Accelerated Transcranial Magnetic Stimulation (TMS) for Smoking Cessation in People Living With HIV/AIDS (PLWHA)
Source: ClinicalTrials.gov · Last updated 22 Oct 2025
Brief summary (registry, in English)
To demonstrate whether four sessions of TBS improves attentional bias and craving in PLWHA smokers compared to four sessions of sham stimulation. We hypothesize 4 sessions of TBS to the left DLPFC will significantly improve attentional bias and craving for smoking cues compared to neutral cues in a population of subjects who are smokers with HIV/AIDS compared to sham stimulation.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 4 (actual)
- First submitted
- 10 Feb 2022
- Start date
- 1 Apr 2022
- Primary completion date
- 31 Jul 2024
- Lead sponsor
- Gopalkumar Rakesh
- Diseases
- HIV
- NCT number
- NCT05295953
What you commit to
- Study type: Interventional
- Participants enrolled: 4
- From 1 Apr 2022 to the primary completion date, 31 Jul 2024
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous adverse effect with TMS.
Other illness
- Positive pregnancy test for females, traumatic brain injury, history of seizure disorder, history of or current diagnosis of schizophrenia, intracranial metal shrapnel.
- Failure to show baseline attentional bias to smoking versus neutral cues.
Other
- Sub-threshold consistency while performing behavioral tasks.
Who the study is looking for
- Patients enrolled in the Bluegrass Clinic
- 18-60 years of age
- Male or female gender
- Able to read, understand and communicate in English
- Willing to adhere to the general rules of the Bluegrass Clinic/SMARTClinic/Beyond Birth Clinic
- Willing and able to abstain from drug use other than Suboxone
- Exhaled breath on day of study carbon monoxide (CO) \< 5 ppm
- Stabilized on maintenance buprenorphine if having comorbid opioid use disorder.
Age in the registry: 18 years to 60 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| 245 Fountain Court Coordinator of this site? Confirm its status | Lexington | United States | Unknown status |
| University of Kentucky Coordinator of this site? Confirm its status | Lexington | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.