NCT05296720Recruiting
EEG and Behavioral Correlates of Temporal Prediction in the Tactile Modality in Schizophrenia
Source: ClinicalTrials.gov · Last updated 25 Mar 2026
Brief summary (registry, in English)
Patients with schizophrenia have disturbances in their sense of self, particularly their bodily self. Disorders of the sense of self are central to schizophrenia and are of interest because they are thought to be present prior to the development of the disorder, when only a few attenuated symptoms signal a risk of developing psychosis. Finding markers related to the sense of self would make it possible to predict which subjects, among those with minimal psychotic symptoms, will develop psychosis, and thus to better adapt management. Disturbances in the experience of the passage of time that accompany disturbances in the sense of self have been described particularly in subjects at risk of developing psychosis, and would predict the onset of the pathology. However, as with alterations in the sense of self, it can be difficult to get patients to describe their disturbances in the experience of time, and objective measures are required to facilitate detection of these disturbances. In the present protocol an objective measure of temporal perception mechanisms will be tested in relation to the sense of self. The tests used in the protocol assess subjects' abilities to benefit from the passage of time and to use these abilities to predict and prepare for the occurrence of an event. The investigators have previously shown that patients with impaired bodily sense of self do not benefit from the passage of time to prepare themselves to process information in the future. The present protocol is aimed at developing a measure more sensitive to the patients' disorders by adding tactile measures.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 68 (estimated)
- First submitted
- 17 Feb 2022
- Start date
- 13 Apr 2023
- Primary completion date
- Apr 2027
- Lead sponsor
- Centre Psychothérapique de Nancy
- Diseases
- Schizophrenia
- NCT number
- NCT05296720
What you commit to
- Study type: Interventional
- Planned participants: 68
- From 13 Apr 2023 to the primary completion date, Apr 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of benzodiazepines (in the period prior to inclusion, for a duration equivalent to 5 half-lives of the product), cannabis (in the 2 months prior to inclusion; use of cannabis (THC) will be verified with a urine dipstick) or hallucinogenic substances (in the period prior to inclusion, for a duration equivalent to 5 half-lives of the product);
Other illness
- Psychoactive substance use disorders (as defined by DSM-V);
- Attention deficit hyperactivity disorder (ADHD);
- A borderline personality disorder;
- Disabling sensory disorders;
Other
- Neurological pathology or sequelae;
- Person deprived of liberty or under court protection;
- Pregnant, parturient or nursing woman;
- Subject in a period of exclusion as defined by another clinical study.
Who the study is looking for
- Male or Female;
- Age between 18 and 60 years inclusive;
- Subject who has dated and signed the consent form (guardian or custodian prior to the commencement of any trial-related procedures if applicable);
- Enrolled in a social security plan or beneficiary of such a plan.
Age in the registry: 18 years to 60 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Anne GIERSCH Coordinator of this site? Confirm its status | Strasbourg | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.