NCT05299749Recruiting
Real-time fMRI Neurofeedback in Patients With Schizophrenia and Auditory Hallucinations
Real-time fMRI Neurofeedback as a Tool to Mitigate Auditory Hallucinations in Patients With Schizophrenia - R33 Phase
Source: ClinicalTrials.gov · Last updated 18 Sept 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Neurofeedback intervention aimed to regulate the superior temporal gyrus (STG) activation and default mode network (DMN) connectivity as well as to reduce the auditory hallucinations (AH) schizophrenia patients with medication resistant AH.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 104 (estimated)
- First submitted
- 8 Mar 2022
- Start date
- 1 Mar 2022
- Primary completion date
- 30 Jun 2026
- Lead sponsor
- Boston VA Research Institute, Inc.
- Diseases
- Schizophrenia
- NCT number
- NCT05299749
What you commit to
- Study type: Interventional
- Planned participants: 104
- From 1 Mar 2022 to the primary completion date, 30 Jun 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- electroconvulsive therapy
- alcohol or drug dependence
- alcohol or drug abuse within the past five years
Other illness
- neurologic illness
Other
- major head trauma
- verbal IQ below 70
Who the study is looking for
- patients diagnosed with SZ or schizoaffective disorder using DSM-5 criteria
- auditory hallucinations not responsive to pharmacology as determined by chart review and a clinical interview of SCID.
Age in the registry: 18 years to 55 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Boston VA Healthcare System, Brockton Coordinator of this site? Confirm its status | Brockton | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.