NCT05301634CompletedPhase 3
Comparison Between Bilateral Infraorbital Block Versus Intranasal Bupivacaine in Transsphenoidal Pituitary Adenoma Resection
Comparison Between Hemodynamic Effect of Bilateral Infraorbital Block Versus Intranasal Application of Bupivacaine in Patients Undergoing Transsphenoidal Pituitary Adenoma Resection.A Comparative Randomized Controlled Study
Source: ClinicalTrials.gov · Last updated 30 Dec 2025
Brief summary (registry, in English)
The study will evaluate the efficacy of bilateral infraorbital nerve block versus preoperative nasal packing with long-acting local anesthetic bupivacaine in term of maintaining hemodynamics intraoperative within 20% below baseline to achieve adequate hypotensive anesthesia and longer duration of postoperative analgesia up to 24 hours in patients undergoing transsphenoidal pituitary adenoma resection.
- Status (registry)
- Completed
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 60 (actual)
- First submitted
- 20 Mar 2022
- Start date
- 2 Apr 2022
- Primary completion date
- 30 Jul 2025
- Lead sponsor
- Cairo University
- Diseases
- High blood pressure
- NCT number
- NCT05301634
What you commit to
- Study type: Interventional · Phase 3
- Participants enrolled: 60
- From 2 Apr 2022 to the primary completion date, 30 Jul 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Allergy to local anesthetics.
- Preoperative cardiac arrythmias.
- Seizure disorders.
- Patients with severe endocrinal disorders that affecting the craniofacial morphology as acromegaly and cushinoid features.
Other
- Patient's refusal
- Preoperative cerebrospinal fluid leak.
Who the study is looking for
- ASA I, II or III
- patients scheduled to undergo endoscopic transsphenoidal approach to remove tumor under general anesthesia
Age in the registry: 21 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Kasr Alaini hospital Coordinator of this site? Confirm its status | Cairo | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.