NCT05304039Active, not recruiting
Phenotyping and Classifying Asthma Exacerbations
Phenotyping and Classifying of Childhood and Adult Asthma Exacerbations: Towards Personalised Treatment. An Observational Multicentre Study.
Source: ClinicalTrials.gov · Last updated 21 Aug 2025
Brief summary (registry, in English)
An observational study in patients between 12 and 70 years old with an acute asthma exacerbation, to determine the relation between phenotypical characteristics and the treatment response.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 200 (estimated)
- First submitted
- 22 Mar 2022
- Start date
- 28 Sept 2022
- Primary completion date
- 31 Mar 2025
- Lead sponsor
- Franciscus Gasthuis
- Diseases
- Asthma
- NCT number
- NCT05304039
What you commit to
- Study type: Observational
- Planned participants: 200
- From 28 Sept 2022 to the primary completion date, 31 Mar 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Maintenance medication or recently discontinued (\< 6 weeks) biologicals.
Other illness
- Immunosuppressive maintenance medication (azithromycin, systemic corticosteroids maintenance therapy and other) or recently (\< 6 weeks) discontinued these medications. (Desensitization therapy indicated for allergies can be included in the study)
- Other underlying inflammatory or auto-immune diseases, such as rheumatologic disease.
Other
- Involvement in the planning and/or conduct of the study (applies to both investigator staff and/or staff at the study site)
- Pregnancy, because of the possible altered immunological status.(31)
- Participation in an interventional study or randomised controlled trial.
Who the study is looking for
- Patient diagnosed with asthma according to the GINA guidelines between 12 and 70 years old. If patients are doctor's diagnosed with asthma based on clinical data, the further diagnostics will be performed to confirm the asthma diagnosis after the AAE.
- Mild to severe asthma, treated according to GINA guidelines with medium - or high dose inhaled corticosteroids (with or without LABA) or treated with a low dose inhaled corticosteroids combined LABA or leukotriene - receptor antagonist.
- Asthma exacerbation, indicated for systemic corticosteroids.
- Written personal and/or parental informed consent, prior to any study procedures.
- Eligibility and willingness to present during an asthma exacerbation at the Franciscus Gasthuis hospital.
- Ability to use e - health applications.
Age in the registry: 12 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Franciscus Gasthuis & Vlietland Coordinator of this site? Confirm its status | Rotterdam | Netherlands | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.