NCT05308914Completed
Self-Management and Resilience Trajectories in African American Adults With Hypertension
Source: ClinicalTrials.gov · Last updated 15 May 2026
Brief summary (registry, in English)
Hypertension (HTN) rates have increased worldwide, but the most significant increase in the incidence of morbidity and mortality has been in African Americans (AA) (43% vs 27% for other U.S. population groups). Despite evidence of positive benefits from lifestyle modification (healthy diet, reduced sodium intake, increased physical activity, smoking cessation) and prescribed antihypertensive therapy (AHT) many AA with HTN do not adhere to their treatment regimens. Consistent, effective lifelong self-management is required to sustain optimal BP control and thus reduce morbidity and mortality. Self-managing HTN to a blood pressure (BP) \<130/80 mm Hg presents challenges such as juggling multiple medications and health care providers, dealing with complex recommendations and treatment regimens, and coping with negative emotional states. Few studies have examined the biopsychosocial mechanisms that foster effective HTN self-management and resilience among AA living with HTN. Understanding the mechanisms that influence HTN self-management and resilience in AA holds the promise of new modifiable targets for behavior-change interventions. This study explores the relationship among resilience precursors on hypertension (HTN) self-management behaviors, stress response, and the effects that these relationships have on health outcomes-health-related quality of life (HRQOL) and blood pressure (BP) in African Americans (AA) with HTN over a 6-month period.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 125 (actual)
- First submitted
- 9 Mar 2022
- Start date
- 1 Mar 2022
- Primary completion date
- 21 Mar 2025
- Lead sponsor
- Case Western Reserve University
- Diseases
- High blood pressure
- NCT number
- NCT05308914
What you commit to
- Study type: Observational
- Participants enrolled: 125
- From 1 Mar 2022 to the primary completion date, 21 Mar 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Have experienced a major CVD event or procedure (e.g., myocardial infarction, stroke, heart surgery) within the past year
Other
- Unable to give informed consent or judged to have impaired cognitive ability or severe memory
Who the study is looking for
- Self-identify as African American
- 25 years of age or older
- Diagnosed with hypertension and prescribed one antihypertensive medication
- BP \>130/80 mmHg
- Have at least one additional chronic health conditions
- Able to read/understand English
Age in the registry: 25 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospitals Cleveland Medical Center* Coordinator of this site? Confirm its status | Cleveland | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.