NCT05309369Completed
Musical Engagement of Brain LObes in Alzheimer's Disease Patients StudY
Source: ClinicalTrials.gov · Last updated 9 Sept 2025
Brief summary (registry, in English)
This is a randomized, cross-over study to measure global and clinical impact and level of arousal in subjects suffering from moderate to severe Alzheimer's disease when exposed to emotionally impactful music compared to control intervention.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 10 (actual)
- First submitted
- 25 Mar 2022
- Start date
- 11 May 2022
- Primary completion date
- 15 Mar 2024
- Lead sponsor
- Medical University of South Carolina
- Diseases
- Alzheimer disease
- NCT number
- NCT05309369
What you commit to
- Study type: Interventional
- Participants enrolled: 10
- From 11 May 2022 to the primary completion date, 15 Mar 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Suffer from severe hearing impairment as reported by the informant
- Presence of neuropsychiatric symptoms of dementia as determined by clinical observation by the Principal Investigator, including history of agitation and/or combative behavior.
Other
- Individuals who score ≥ 12 seconds on the Timed Up and Go (TUG) Test.
Who the study is looking for
- Provision of signed and dated informed consent form
- Person of any sex/gender aged between 55 and 90
- Stated willingness to comply with all study procedures and availability for the duration of the study
- In the opinion of the investigator, has an informant able and willing to provide accurate information about the participant (may be paid or unpaid caregiver)
- Suffer from moderate to severe Alzheimer's disease as established by the study team using the National Institute of Neurological and Communicative Diseases and Stroke/Alzheimer's Disease and Related Disorders Association (NINCDS-ADRDA) Alzheimer's Criteria for possible and probable Alzheimer's Disease
- Diagnosis of Alzheimer's disease or other type of dementia as defined by the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V)
- Mini Mental State Examination (MMSE) score of 5-20
- Subject is reported by the study partner to be able to listen to a minimum of 10 minutes of music and a sound in an uninterrupted manner.
Age in the registry: 55 years to 90 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Medical University of South Carolina Coordinator of this site? Confirm its status | Charleston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.