NCT05317286Completed
LVEF Prediction During ACS Using AI Algorithm Applied on Coronary Angiogram Videos
Prospective Validation of a Deep Learning Algorithm for Prediction of the Left Ventricular Ejection Fraction From Coronary Angiogram Videos in Patients With Acute Coronary Syndrome
Source: ClinicalTrials.gov · Last updated 12 Mar 2024
Brief summary (registry, in English)
Left ventricular ejection fraction (LVEF) is one of the strongest predictors of mortality and morbidity in patients with acute coronary syndrome (ACS). Transthoracic echocardiography (TTE) remains the gold standard for LVEF measurement. Currently, LVEF can be estimated at the time of the coronary angiogram but requires a ventriculography. This latter is performed at the price of an increased amount of contrast media injected and puts the patients at risk for mechanical complications, ventricular arrhythmia or atrio-ventricular blocks. Artificial intelligence (AI) has previously been shown to be an accurate method for determining LVEF using different data sources. Fur the purpose of this study, we aim at validating prospectively an AI algorithm, called CathEF, for the prediction of real-time LVEF (AI-LVEF) compared to TTE-LVEF and ventriculography in patients undergoing coronary angiogram for ACS.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 240 (actual)
- First submitted
- 22 Mar 2022
- Start date
- 1 Jun 2022
- Primary completion date
- 31 Dec 2023
- Lead sponsor
- Montreal Heart Institute
- Diseases
- Coronary artery disease
- NCT number
- NCT05317286
What you commit to
- Study type: Observational
- Participants enrolled: 240
- From 1 Jun 2022 to the primary completion date, 31 Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Lab values
- Creatinine clearance \<30 ml/min/m2 according to MDRD
Other
- No indication to perform TTE in the 7 days following coronary angiogram
- Right bundle branch block
- Suspected or confirmed left ventricular thrombus
- Suspected or confirmed aortic dissection
- Ventriculography not feasible
- No left coronary system angiogram
Who the study is looking for
- Informed consent signed by the participant
- Acute coronary syndrome
- Creatinine clearance ≥30 ml/min/m2 according to MDRD
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Robert Avram Coordinator of this site? Confirm its status | Montreal | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.