NCT05326477Recruiting
Predictors of Behavioral Obesity Treatment Outcomes
Source: ClinicalTrials.gov · Last updated 11 Mar 2026
Brief summary (registry, in English)
Socioceconomically disadvantaged individuals typically have poor outcomes in behavioral weight loss interventions, but the reasons for this are unknown. This project will characterize the mechanisms through which adverse daily experiences and present bias -- a cognitive adaptation to harsh and unpredictable environments -- account for disparities in weight loss outcomes.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 230 (estimated)
- First submitted
- 6 Apr 2022
- Start date
- 26 May 2023
- Primary completion date
- 30 Jun 2027
- Lead sponsor
- Rush University Medical Center
- Diseases
- Obesity
- NCT number
- NCT05326477
What you commit to
- Study type: Interventional
- Planned participants: 230
- From 26 May 2023 to the primary completion date, 30 Jun 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous or planned bariatric surgery, or concurrent engagement in other behavioral or pharmacological treatment for obesity
Other illness
- History of bariatric surgery, or current engagement in another weight loss therapy
Lab values
- Medical contraindications to treatment, including osteoporosis, cognitive impairment (Montreal Cognitive Assessment ≤25), active substance abuse based on the World Health Organization's ASSIST screener, lack of physician clearance for participation, or serious medical illness (e.g., stage 3 or 4 heart failure, cancer, renal failure, etc.)
Other
- Not fluent in English
- Change in income or financial assets exceeding ±75% of federal poverty guideline within the past 12 months, or expected in the next 6 months, if this change would result in reclassification on SES.
- Resides more than 20 miles away from Rush, or planning to move outside of this geographic area during the study period
- Body mass index ≥60 kg/m2, due to increased injury risk with exercise
- Lack of reliable access to cell or landline phone
Who the study is looking for
- Age ≥18 years old
- Obesity (body mass index ≥30 kg/m2)
- Meets criteria for either the lower SES or higher SES cohort
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Rush University Medical Center Coordinator of this site? Confirm its status | Chicago | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.